Cephalexin Manufacturer CAS:15686-71-2

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10 Gram	Negotiable

10 Gram

Negotiable

Min.Order :10 Gram
Purity: 99%
Payment Terms : T/T,

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99% Cephalexin Cephalexin Manufacturer Antibiotic

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Appearance:White Powder
Application: It Can Be Used As Pharmaceutical Intermediates, Or As Curing Agent Of Epoxy Resins, Etc
PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
ProductionCapacity:10000|Metric Ton|Month
Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

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Cephalexin Basic information

Description Indications Mechanism of Action Pharmacodynamics Interactions Uses Dosing Information Elimination Side effects Safety Precautions

Product Name:	Cephalexin
Synonyms:	(6r-(6alpha,7beta(r*)))-ino)-3-methyl-8-oxo;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((aminophenylacetyl)am;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-(2-amino-2-phenylaceta;7-(d-2-amino-2-phenylacetamido)-3-methyl-delta(sup3)-cephem-4-carboxylica;7-(d-2-amino-2-phenylacetamido)-3-methyl-delta3-cephem-4-carboxylicacid;7-(d-alpha-aminophenylacetamido)desacetoxycephalosporanicacid;7-beta-(d-alpha-amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxyli;cefa-iskia
CAS:	15686-71-2
MF:	C16H17N3O4S
MW:	347.39
EINECS:	239-773-6
Product Categories:	Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Interferes with Cell Wall SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity;Pharma;cephalosporins;Cefalexin, Alcephin, Cefablan, keflex,Cefadin, Tepaxin;Pharmaceutical intermediates
Mol File:	15686-71-2.mol

Cephalexin Chemical Properties

Melting point	196-198°C
density	1.3040 (rough estimate)
refractive index	1.6320 (estimate)
storage temp.	2-8°C
solubility	NH₄OH 1 M: 50 mg/mL, clear, yellow
pka	5.2, 7.3(at 25℃)
Merck	13,1986
InChIKey	AVGYWQBCYZHHPN-CYJZLJNKSA-N
CAS DataBase Reference	15686-71-2(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	22-36/37-45
WGK Germany	3
RTECS	XI0350000
HS Code	29419000
Hazardous Substances Data	15686-71-2(Hazardous Substances Data)

Cephalexin Usage And Synthesis

Description	Cephalexin is a cephalosporin antibiotic that is used to examine the impact of binding, expression, and inhibition of PBP3 as well as additional penicillin-binding proteins (PBPs) on the cell wall during bacterial mucopeptide synthesis. Cephalexin is used for the treatment of infection-causing bacteria that may induce ear, respiratory, urinary tract, and skin infections. Bacteria that are defenseless against Cephalexin may include Streptococcus pneumonia, Staphylococcus aureus, E. coli, and Haemophilus influenza. Cephalexin is also referred to as Keflex (brand name), and it does not relieve viral infections such as flu or colds.
Indications	Cephalexin is prescribed for the treatment of otitis media, genitourinary, bone, respiratory, and skin structure infections.
Mechanism of Action	The mechanism of action of Cephalexin resembles that of penicillin where it inhibits synthesis of the bacterial cell wall, its absence influences death as a result of bacterial lysis. Cell lysis is further mediated by autolytic enzymes particular to the bacterial cell wall, which includes autolysis. Research indicates that there is a probability that Cephalexin impedes the functionality of an autolysin inhibitor.
Pharmacodynamics	Cephalexin is a 1^st generation cephalosporin antibiotic that is widely prescribed for the treatment of external infections that may arise from complications associated with lacerations or minor wounds. The drug is effective in fighting a majority of gram-positive bacteria. Cephalexin illustrates vitro activity that opposes methicillin-susceptible Staphylococcus aureus, a notable pathogen in osteoarticular infections. However, pharmacodynamics and pharmacokinetics are inadequately defined in children.
Interactions	Cephalexin may minimize the impact of typhoid and BCG vaccines. Notably, these three drugs should not be administered at the same time. Patients are also advised to take the drug on an empty stomach at least 1-2 hours after meals.
Uses	Cephalexin is administered to minimize the development of bacteria that are resistant to drugs. To maintain the overall effectiveness of Cephalexin, the drug should be prescribed as a treatment for infections that can be attributed to bacteria. The availability of susceptibility and culture information should be put into consideration while making modifications to antibacterial therapy. The absence of such information may be backed by susceptibility and epidemiology patterns to influence verifiable adoption of treatment. In some cases, Cephalexin is used for the treatment of patients who are allergic to penicillin and may have a heart condition at the time when they are undergoing a procedure on their respiratory tract, to inhibit the development of infection on their heart valves.
Dosing Information	A standard dose of Cephalexin should be administered orally in 250mg every 6 hours. Alternatively, in 12 hours, a dose of 500mg should be administered to the patient during the 7-14days treatment period. In instances where the infections are severe, higher doses up to 4g should be administered in 2-4 equal does every day. For pediatric patients, the appropriate daily dose of Cephalexin is 25-40mg/kg administered in equal doses for a period of 7-14days. Severe infections may necessitate 50-100mg/kg administered in equal doses. The treatment of Otitis media necessitates 75-100mg/kg in equal doses of Cephalexin. For patients with renal impairments, the dosage requirements may be adjusted accordingly for both pediatric and adult patients.
Elimination	Cephalexin undergoes tubular secretion and glomerular filtration before it is eliminated in urine. Studies indicate that about 90% of Cephalexin is eliminated in its unaltered form in urine within 8 hours.
Side effects	Allergic reactions to Cephalexin may result in respiratory issues, swelling of the tongue, lips, face, or the throat, and hives. Nonetheless, one may need to consult a doctor if they experience watery diarrhea or intense stomach pains, unusual bleeding or easy bruising, minimal or no urination, hallucinations, confusion or agitation, and severe skin reaction. Common side effects associated with Cephalexin include vaginal discharge or itching, skin rash, fever, nausea, vomiting, joint pain, headache, feeling of exhaustion, dizziness, or diarrhea.
Safety Precautions	A patient should inform the pharmacist or doctor of any allergic reactions to Cephalexin, associated cephalosporin antibiotics, and additional ingredients or medications. The patient should also indicate any nutritional supplements, vitamins, herbal products or medications they are taking or they are planning to take. It is important to notify the doctor of a preexisting liver, kidney or gastrointestinal disease, especially colitis, if one is either pregnant or planning on getting pregnant, and if they conceive while taking Cephalexin. If Cephalexin is prescribed to a patient with no clear indications of a bacterial infection, there are minimal chances that the drug will benefit the patient. Instead, it will increase the patient’s chances of developing drug-resistant bacteria. Using Cephalexin over extended periods of time may induce the overgrowth of non-susceptible organisms. Doctors should examine their patients for superinfections during therapy for the implementation of appropriate treatment measures.
Chemical Properties	White cryst. powder

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