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5-Fluorouracil factory 51-21-8 in China Hot sale 51-21-8
5-Fluorouracil factory 51-21-8 in China
Product name :5-Fluorouracil
5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase.
Synonyms
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidine-2,4-dione
CAS No. 51-21-8
EINECS 200-085-6
Molecular formula C4H3FN2O2
Molecular weight 130.08
Appearance
White to off- white crystalline powder
Melting point 278-286 ºC
Boiling point 401.4 °C at 760 mmHg
Assay 99%mmin
Packing
25Kg/drum or as required
Application
Used for digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, bladder cancer and skin cancer treatment
Synchem is dedicated to custom synthesis and manufacturing services for small molecules. We specialize in advanced fluorinating techno-logy, asymmetrical catalysis technology, and highly effective organic-metal catalysis technology.
Certification Name |
Certified By |
Certificate No. |
Product Name & Model No. |
Available Date --- Expired Date |
ISO |
Transpacific Certifications Limited | ISO 9001:2008 |
Scope of Inspection: The Production, R&D,Pilot, Sales and Techology service of Liquid Crystal Intermediates, Liquid Crystal Monomer and Pharmaceutical Intermediates |
2014/05/31---2017/05/30
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5-Fluorouracil factory 51-21-8 in China
Product Description:
Fluorouracil has been given systemically for anal, breast,colorectal,oesophageal,stomach, pancreatic and skin cancers (especially head and neck cancers).It has also been given topically for actinic keratoses and Bowen's disease.
Product Name | 5-Fluorouracil |
Appearance | Off-white powder |
CAS NO. | 51-21-8 |
Molecular Formula | C4H3FN2O2 |
Molecular Weight | 130.08 |
Density | 1.53 g/cm3 |
Melting Point | 278-286ºC |
Boiling Point | 401.4ºC at 760 mmHg |
Flash Point | 196.5ºC |
Assay | 99% min |
Function:
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.
Application:
1. It is used for biochemical studies and antitumor drugs.
2. It is the anti tumor drug, also used for synthesis of flucytosine. 5- fluorouracil can be used in the study of rice in the biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.
3. It is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, treatment of bladder cancer and skin cancer.
4. Antimetabolite antitumor drugs.
5. Anti tumor drugs. There is a certain effect on a variety of tumors such as digestive tract cancer, breast cancer, ovarian cancer, chorionic epithelial cancer, cervical cancer, hepatocellular carcinoma, bladder cancer, skin cancer (topical), leukoplakia (topical) etc. Adverse reactions mainly are bone marrow transplantation, digestive tract reaction, serious person can have diarrhea, local injection site phlebitis, a few of which have nervous system reactions such as cerebellar degeneration and ataxia. The course of medication should strictly check the blood.
Why Choose China Synchem
1. Quality
Our products meet MSDS safe standard and we have ISO and other certificate so yan can get high quality products from our company.
2. Price
We are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3. Packing
We can do according to the customers' request.
4. Transport
The products can be transported by Courier, by air or by sea
5. Service
We offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
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