CasNo.405165-61-9,Besifloxacin HCl,(405165-61-9) Suppliers

1 Kilogram	FOB Price: USD 1.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : T/T,,MoneyGram,Other

Keywords

405165-61-9 C19H21ClFN3O3.ClH Besifloxacin hydrochloride

Quick Details

Appearance:White powder
Application:Pharmaceutical Intermediates
PackAge:carton boxes or fibre drums
ProductionCapacity:100|Kilogram|Month
Storage:Keep in cool and dry place
Transportation:by Air or by sea

Superiority:

We focus on high complex new type intermediates and fine chemical custom synthesis,scale-up production and rare chemicals. Product category including intermediates&api,catalyst and electronic chemicals.

We have our R&D team and can supply custom made service for chemicals , and keep good relationship with some pharmaceutical companies. Our synthesis level is well-known to the industry, the products are exported to US, France,Poland,Czech,Ukraine,Spain,Switzerland etc.

Our Company facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Career Chemical have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.

Details:

Besifloxacin hydrochloride Basic information

Outline Besifloxacin hydrochloride ophthalmic suspension

Product Name:	Besifloxacin hydrochloride
Synonyms:	Besifloxacin HCl;Unii-7506A6J57t;(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride;Besifloxacin hydrochloride;(R)-7-(3-AMinohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinolin-3-carboxylic acid HCl;3-Quinolinecarboxylic acid, 7-[(3R)-3-aMinohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, Monohydrochloride (9CI);(R)-7-(3-aMinoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;7-[(3R)-3-AMinohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Hydrochloride
CAS:	405165-61-9
MF:	C19H21ClFN3O3.ClH
MW:	430.305
EINECS:	1312995-182-4
Product Categories:	Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors;API
Mol File:	405165-61-9.mol

Besifloxacin hydrochloride Chemical Properties

Melting point	>210°C (dec.)
storage temp.	Refrigerator

Besifloxacin hydrochloride Usage And Synthesis

Outline	Besifloxacin hydrochloride is developed by Bausch & Lomba as a new type of fluoroquinolones for the treatment of bacterial conjunctivitis (a non-viral caused infectious purulent eye irritation conjunctivitis ). Bacterial conjunctivitis which is a contagious eye disease, is a common disease that affects people of all ages. The clinical symptoms of infested eye including: foreign body sensation, burning sensation, tearing; conjunctival hyperemia, mucus or purulent discharge; eyelid edema, conjunctival edema and subconjunctival hemorrhage may occur in severe cases .
Besifloxacin hydrochloride ophthalmic suspension	Besifloxacin hydrochloride ophthalmic suspension (Besivance) is a fluoroquinolone drug recently approved for the topical treatment of bacterial conjunctivitis. This medicine can quickly kill common pathogens causing conjunctivitis , that is coagulase-negative staphylococci, Streptococcus pneumoniae, Staphylococcus aureus , Haemophilus influenzae bacteria, and other less common bacteria.. Besifloxacin is an effective drug to the Gram-positive and Gram-negative pathogens, include other fluoroquinolone-resistant bacteria , also it can balance the DNA gyrase and topoisomerase IV activity, slow the development of resistance. Topical administration can achieve stable and lasting high concentrations in human tears , and penetration in animal ocular tissue is good, showing excellent safety. Pharmacokinetic and pharmacodynamic characteristics of Besifloxacin meet the criteria for successfully clearing most Gram-positive and Gram-negative bacteria, while exhibiting minimal systemic exposure.Besifloxacin biochemical properties, pharmacokinetics targeted to achieve/pharmacodynamic objectives and limited to local ophthalmic drug will slow the development of bacterial resistance, making Besifloxacin become attractive choice for acute bacterial conjunctivitis treatment. The above information is edited by the chemicalbook of Tian Ye.
Chemical Properties	Pale Yellow Solid
Uses	Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic
Uses	A Fluoroquinolone antibiotic.