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100 Kilogram |
Negotiable |
white-Light yellow powder 95-25-0 global 95-25-0 imformation of Chlorzoxazone
white-Light yellow powder 95-25-0 imformation of global |
Melting point | 191-192 °C(lit.) |
density | 1.3771 (rough estimate) |
refractive index | 1.5557 (estimate) |
storage temp. | -20°C Freezer |
solubility | DMSO: soluble50mg/mL, clear |
form | Powder |
color | white to off-white |
Water Solubility | 0.1 g/100 mL |
Merck | 14,2194 |
CAS DataBase Reference | 95-25-0(CAS DataBase Reference) |
NIST Chemistry Reference | Chlorzoxazone(95-25-0) |
EPA Substance Registry System | 2(3H)-Benzoxazolone, 5-chloro-(95-25-0) |
Chlorzoxazone
Characters: White or white crystalline powder.
Standard: USP34
【Package】25KG/DRUM
Pharmacological effects: This product is a central muscle relaxant.
It is a major role in the central nervous system,
suppress reflex arc in the spine and brain cortex,
Muscle relaxation effect on spastic skeletal muscle to achieve the analgesic effect.
Indications: For a variety of acute and chronic soft tissue (muscles,ligaments, fascia) sprains,
contusions, pain caused by muscle strain after exercise;
muscle spasms, chronic fasciitis caused by CNS lesions.
white-Light yellow powder 95-25-0 imformation of global
Chlorzoxazone
Characters: White or white crystalline powder.
Standard: USP34
【Package】25KG/DRUM
Pharmacological effects: This product is a central muscle relaxant.
It is a major role in the central nervous system,
suppress reflex arc in the spine and brain cortex,
Muscle relaxation effect on spastic skeletal muscle to achieve the analgesic effect.
Indications: For a variety of acute and chronic soft tissue (muscles,ligaments, fascia) sprains,
contusions, pain caused by muscle strain after exercise;
muscle spasms, chronic fasciitis caused by CNS lesions.
Chlorzoxazone Usage And Synthesis
Pharmacokinetics |
This product can be completely absorbed by the digestive tract with the plasma concentration reaching peak at 1.5-2 hours. It is distributed in muscle, kidney, liver, brain and fat. After 6 hours, the drug concentration decreases significantly. Almost all of the goods can subject to in vivo catabolism with the elimination half-life being about 1 hour. This information is edited by Xiongfeng Dai from Chemicalbook. |
Indications | Chlorzoxazone is suitable for the treatment of various kinds of acute and chronic soft tissue (muscles, ligaments and fascia) sprain, contusion, muscle pain after exercise, pain caused by muscle strain and the muscle spasms caused by the central nervous system lesions as well as chronic fasciitis. |
Chlorzoxazone synthesis |
Take 2, 5-dichloro-nitrobenzene as raw material; go through hydrolysis, reduction reaction to give 2-amino-4-chloro-phenol, followed by cyclization reaction in hydrochloric acid to obtain the finished product of Chlorzoxazone with the total yield being 84%. |
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