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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8 C40H80NO8P
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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Basic information |
Product Name: | 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE |
Synonyms: | 16:0 PC;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE;1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;L-A-LECITHIN DIPALMITOYL;L-ALPHA-DIPALMITOYL PHOSPHATIDYLCHOLINE;L-ALPHA-LECITHIN, DIPALMITOYL |
CAS: | 63-89-8 |
MF: | C40H80NO8P |
MW: | 734.04 |
EINECS: | 232-642-4 |
Product Categories: | Amines;Fatty Acid Derivatives & Lipids;Glycerols;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents |
Mol File: | 63-89-8.mol |
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties |
Melting point | 229-229.5 °C |
alpha | D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol) |
storage temp. | −20°C |
Merck | 14,2477 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 63-89-8(CAS DataBase Reference) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
ACROS | English |
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Usage And Synthesis |
Chemical Properties | white powder |
Uses | Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity). |
Definition | ChEBI: A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants. |
Purification Methods | It has three crystalline forms 1, 2 and ' which change at 60-70o and at 229o, respectively. In order to obtain a fine powder, ~2 g are dissolved in CHCl3 (15mL) and pet ether (b 35-60o) is added; the solution is evaporated to dryness in vacuo at <20o and then dried at 0.1mm over CaCl2. [Baer & Maurukas J Am Chem Soc 74 158 1952, Baer & Kates J Biol Chem 185 615 1950, Beilstein 4 IV 1463.] |
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials |
Raw materials | TYLOXAPOL |
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