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Formoterol fumarate Basic information |
Product Name: | Formoterol fumarate |
Synonyms: | formamide,n-(2-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amin;o)ethyl)phenyl)-,(e)-2-butenedioate(2:1)(salt),dihydrate;FORMOTEROL FUMARATE;FORMOTEROL HEMIFUMARATE;n-[2-hydroxy-5-[[(1rs)-1-hydroxy-2-[[(1rs)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide (e)-2-butenedioate;(+/-)-(R*,R*)-N-[2-HYDROXY-5-[1-HYDROXY-2-[[2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO]ETHYL]PHENYL] FORMAMIDE HEMIFUMARATE;(R*,R*)-(+)-N-[2-HYDROXY-5-[1-HYDROXY-2-[[2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO]ETHYL]-PHENYL]FORMAMIDE FUMARATE;(R*,R*)-N-[2-HYDROXY-5-[1-HYDROXY-2-[[2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO]ETHYL]PHENYL]FORMAMIDE FUMARATE |
CAS: | 43229-80-7 |
MF: | C42H52N4O12 |
MW: | 804.88 |
EINECS: | 1308068-626-2 |
Product Categories: | APIs;Active Pharmaceutical Ingredients;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Adrenoceptor;Analgesics;Inhibitors |
Mol File: | 43229-80-7.mol |
Formoterol fumarate Chemical Properties |
Melting point | 138-140°C |
pka | pKa1 7.9; pKa2 9.2(at 25℃) |
λmax | 284nm(lit.) |
Merck | 14,4245 |
Safety Information |
RIDADR | 3249 |
RTECS | LQ2988000 |
HazardClass | 6.1(b) |
PackingGroup | II |
Toxicity | LD50 in male, female, rats, mice (mg/kg): 3130, 5580, 6700, 8310 orally; 98, 100, 72, 71 i.v.; 1000, 1100, 640, 670 s.c.; 170, 210, 240, 210 i.p. (Yoshida) |
Formoterol fumarate Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Uses | antiasthmatic; 2-agonist |
Uses | long-acting β 2-agonist, anti-asthmatic |
Uses | A potent β2-AR agonist |
Uses | A selective 2-adrenergic receptor agonist. Used as an antiasthmatic |
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