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Tacrolimus powder 104987-11-3 Tacrolimus supplier
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Pharm high quality 99% Tacrolimus powder CAS 104987-11-3
Name:Tacrolimus
Molecular Formula : C44H69NO12
Molecular Weight : 804.02
CAS:104987-11-3
Item |
Specifications |
|
Appearance |
White crystalline powder |
|
Identification
|
A: IR
|
The infrared absorption spectrum corresponds to that of tacrolimus CRS |
B: HPLC
|
The retention time of the acrolimus peak of the sample solution corresponds to that of the standard solution, as obtained in the assay |
|
Related Substances |
Impurity RRT0.9 |
≤0.8% |
Impurity RRT1.2 |
≤0.8% |
|
Any other largest impurity |
≤0.1% |
|
Total impurities |
≤0.5% |
|
Isomer |
≤0.5% |
|
Residual Solvents |
Acetone |
≤5000ppm |
Ethanol |
≤5000ppm |
Introduction
Name |
Tacrolimus (FK506) |
Alias |
FK506 |
Molecular Formula |
C44H69NO12 ·H2O |
Molecular Weight |
822.04 |
Quality Standard |
In-house Standard, Assay: >99.0% |
Package Size |
Aluminium bag; Weight: Net weight 50g/bag and 100g/bag |
Brief Introduction |
Tacrolimus is a macrolide immunosuppressant produced by Streptomyces tsukubaensis. Tacrolimus is used to prevent rejection of organ transplants. Tacrolimus is 10 to 100 times superior to cyclosporin in improving graft survival and preventing acute rejection after transplantation, but decreasing the toxin side effects. |
Function
1) Anti-rejection in organ transplantation
2) Treatment of skin diseases. like atopic dermatitis (AD), systemic lupus erythematosus (SLE), autoimmune eye disease and other autoimmune diseases
Application
For medical use.
Specification
ANALYSIS |
SPECIFICATION |
RESULTS |
Appearance |
White powder |
Complies |
Odor |
Characteristic |
Complies |
Assay (HPLC) |
≥98% |
98.5% |
Sieve analysis |
NLT 95% pass 80 mesh |
Complies |
Loss on Drying |
≤2.0% |
1.95% |
Ash |
≤5.0% |
2.15% |
Heavy Metal |
|
|
Pb |
<2ppm |
Complies |
As |
<2ppm |
Complies |
Hg |
<2ppm |
Complies |
Residual Solvent |
Eur.Pharm |
Complies |
Microbiology |
|
|
Total Plate Count |
<1000cfu/g |
Complies |
Yeast & Moulds |
<100cfu/g |
Complies |
E.Coli |
Negative |
Complies |
Salmonella |
Negative |
Complies |
Salmonella |
Negative |
Complies |
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment.
Shipping :
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR
Items |
Specifications |
Appearance |
powder |
Purity (gc area %) |
≥ 98.0% |
H NMR |
Conforms to structure |
Product Description
Certification of Analysis
Items | Index | ||
Appearance | Colorless to light yellow transparent liquid | ||
Solid content % | 30.0 min | 50.0 min | 62.0-64.0 |
Free monomer (as AA) % | 0.50 max | 0.50 max | 1.0 max |
Density (20℃) g/cm3 | 1.10 min | 1.20 min | 1.20 min |
pH(1% water solution) | 2.5-4.5 | 2.5-4.5 | 2.0-3.0 |
Function&Application
PAA can be used as scale inhibitor and dispersant in circulating cool water systems in power plants, iron & steel factories, chemical fertilizer plants, refineries and air conditioning systems. Dosage should be in accordance with water quality and equipment materials. When used alone, 1-15mg/L is preferred.
Product Description
English name:2-Chloro-5-nitrobenzoic acid
Synonyms:5-nitro-2-chlorobenzoic acid; 2-chloro-5-nitrobenzoate
Molecular Formula:C7H3ClNO4
Molecular Weight:200.5566
CAS Registry Number:2516-96-3
EINECS:219-739-7
Melting point:164-168°C
Boiling point:356.5°C at 760 mmHg
Flash point:169.4°C
Vapour Pressur:1.06E-05mmHg at 25°C
Synonyms : RARECHEM AL BO 0234;2-CHLORO-5-NITROBENZOIC ACID;5-NITRO-2-CHLOROBENZOIC ACID;LABOTEST-BB LT00847209;2-chloro-5-nitro-benzoicaci;6-Chloro-3-nitrobenzoic acid;Benzoic acid, 2-chloro-5-nitro-;2-Chloro-5-nirtrobenzoic acid
Certification of Analysis
Item |
Specification |
Appearance |
light yellow crystalline powder |
Purity |
98.0% min |
Moisture |
0.5% max |
Residue on ignition |
0.1% max |
Heavy Metal |
≤20ppm |
Loss on drying |
5.0% max |
Function&Application
Used to synthesize 2-chloro-5-aminobenzoic acid, 5-nitrosalicylic acid, ester and amide intermediates.Used as intermediate of pesticide, medicine and organic pigment.
Product Description
English name: DL-Leucine
CAS No.:328-39-2
Formula: C6H13NO2
Molecular Weight: 131.17 .
Synonyms: Leucine, DL- (8CI);NSC 9252;2-Amino-4-methylvaleric acid;Pentanoic acid, 2-amino-4-methyl-;Valeric acid, 2-amino-4-methyl-;α-Aminoisocaproic acid;α-Amino-γ-methylvaleric acid;
EINECS: 206-328-2
Density: 1.036 g/cm3
Melting Point: 293-296 °C (subl.)(lit.)
Boiling Point: 225.772 °C at 760 mmHg
Flash Point: 90.344 °C
Solubility: soluble in water
Appearance: white crystalline powder
Loss on drying:≤0.2%
Heavy metal(bp):≤15ppm
Purity:≥99%
Application: Pharmaceutical Intermediates.
Certification of Analysis
Function&Application
Function
Supports extreme muscle growth
Builds strength and tremendous power
Timed release to support anti-catabolic effects
Support increased strength and mass
Support improved recovery and reduced soreness
Promote increased endurance exercise capacity
Provides support against catabolism.
Application
1. Skin Care: This product applied on the human skin is with the function of moisturizing, anti-wrinkle, adding nutrition,which is used fr the raw material of high quality mask, moisturizer and cleanser ,can also be used for shampoo and hair care products, bath liquid and so on.
2. Medicines and Health Products :
This product can improve body metabolism, immune function, inhibit cancer cells, activated cells.it has significant function in delaying the human aging, preventing osteoporosis.
3. Food: This product can be added to bread, cakes and various snacks, improve food nutrition structure, especially for children and the elderly digestion and absorption.
4. Dairy products: This product can be widely used in milk drinks, fresh milk, yogurt and other liquid dairy products .have the function of anti-whey precipitation, emulsion stability
5. Beverages:This product can be added to a variety of beverages to make high-energy drinks, play a complementary role in the supplemental energy and body building
Product Description
Product Name |
DL-2-Aminobutyric acid |
Synonyms |
DL-2-AMINO-N-BUTYRIC ACID; DL-ALPHA-AMINOBUTYRIC ACID |
CAS No |
2835-81-6 |
MDL number: |
MFCD00008093 |
EINECS number: |
220-616-5 |
MF |
C4H9NO2 |
MW |
103.12 |
Purity |
99%(min) |
Moisture |
0.5%(max) |
Chemical Properties: |
|
Appearence |
white to off-white powder |
mp |
291℃ |
Safety Information: |
|
Hazard Codes |
Xn: Harmful |
Risk Statements |
20/21/22-36/37/38 |
Safety Statements |
22-24/25-36-26 |
Usage: |
Pharmaceutical Intermediates |
Function&Application
DL-2-Aminobutyric acid is widely used in fields of medicine, food processing, industry, etc.
ITEMS |
STANDARD |
TEST RESULT |
Appearance |
White crystalline powder |
Conform |
Odor |
Odorless |
Conform |
Assay |
99%Min |
99.89% |
Loss on drying |
12.0% max |
11.04% |
Residue on ignition |
0.1% max |
0.05% |
Heavy metals |
10ppm max |
<10ppm |
Arsenic (as As) |
1ppm max |
<1ppm |
Total plate count |
1000cfu/g max |
Conform |
Mash size |
80Mesh |
Conform |
Creatine 57-00-1
Certification: | ISO, BRC, KOSHER, HALAL |
Application: | addictive |
Type: | Herbal Extract |
Appearance: | white Powder |
Part Used: | Natural |
Free Sample: | Yes |
Manufacturetype: | Factory |
Resource: | Natural |
Particle: | 100% Pass 80 Mesh |
Storage Method: | Normal |
Extraction Process: | Physical |
Raw Material: | Natural |
Specification: | ISO |
Packaging Material: | Barrel, foil bag,box,drum |
Origin: | shandong China |
Nicotinamide 98-92-0
Sodium picosulfate ( also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery.
Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It takes 12–24 hours to work, since it works in the colon.
Product Name: | Sodium Picosulfate |
CAS Number: | 10040-45-6 |
Formula: | C18H15NO8S2.2Na |
Molecular Weight: | 481.41 |
Solubility: | DMSO 80 mg/mL |
Long-term Storage: | at -20℃ |
HPLC: | Shows Min >98% purity |
H-NMR: | Consistent with structure |
Description: | Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion. |
Stability and Solubility Advice: |
Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month. |
Product Name |
Fluoxetine hydrochloride |
||||||||
Synonyms |
Alpha-(2-methylamino)-ethylbenzenemethanol;ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL ALCOHOL; 3-HYDROXY-N-METHYL-3-PHENYLPROPYLAMINE;3-METHYLAMINO-1-PHENYLPROPANOL;3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL;3-METHYLAMINO-1-PHENYL-1-PROPANOL;N-METHYL-3-PHENYL-3-HYDROXYPROPYLAMINE;N-METHYL-3-HYDROXY-3-PHENYL PROPYLAMINE |
||||||||
CAS |
56296-78-7 |
||||||||
EINECS |
255-679-8 |
||||||||
Molecular formula |
C10H15NO |
||||||||
Molecular Weight |
165.23 |
||||||||
Molecular Structure |
|||||||||
Physical and Chemical Properties |
|
||||||||
General Description |
White or almost white crystalline powder |
||||||||
Usage |
Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine hydrochloride was approved by the U.S. FDA for the treatment of major depressive disorder in December 1987.Fluoxetine hydrochloride is used for the treatment of major depressive disorder obsessive-compulsive disorder (in both adults and children),bulimia nervosa, panic disorder and premenstrual dysphoric disorder.In addition, Fluoxetine hydrochloride is used to treat trichotillomania if cognitive behaviour therapy has been unsuccessful. Fluoxetine hydrochloride is Fluoxetine intermediate |
||||||||
Packing |
25kg/drum |
||||||||
Storage |
Fluoxetine hydrochloride should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
||||||||
Item |
Specification |
||||||||
Appearance |
White or almost white crystalline powder |
||||||||
Impurity A |
≤0.2% |
||||||||
Impurity B |
≤0.10% |
||||||||
Impurity C |
≤0.2% |
||||||||
Any other impurity |
≤0.10% |
||||||||
Total of other impurities |
≤0.3% |
||||||||
Total impurities |
≤1.5% |
||||||||
Loss on drying |
≤ 0.5% |
||||||||
Residue on ignition |
≤ 0.1% |
||||||||
Assay(on dried basis) |
98.00% to 102.00% |
product name |
prilocaine
|
cas | 721-50-6 |
mf |
c13h20n2o
|
mw |
220.31
|
einecs |
211-957-0
|
appearance |
white powder
|
package |
25kg/drum
|
standard | enterprise standard |
assay |
99%
|
grade | medical grade |
melting point |
37-38ºc
|
flash point |
134.3±23.3 °c
|
Product Name: |
Daunorubicin |
CAS: |
20830-81-3 |
MF: |
C27H30ClNO10 |
MW: |
565.99668 |
EINECS: |
244-069-7 |
Daunorubicinis the first generation of anthracycline antitumor antibiotics. The mechanism resembles doxorubicin. As a cycle non-specific chemotherapy drugs, daunorubicin spectrum anti-tumor doxorubicin far more narrow, for Solid Tumors great as doxorubicin and epirubicin.
Daunorubicin is a clinical first-line anti-cancer drug, is widely used in the clinical treatment of cancer. However, in human liver widespread carbonyl reductase 1 daunorubicin can be converted into a new alcohol metabolite daunorubicin alcohol. This new generation of alcohol metabolites not only lower than the anti-tumor activity of daunorubicin, but also toxic to the heart, resulting in myocardial cell injury.
The metabolic characteristics of daunorubicin greatly limits its clinical application. If we can find a carbonyl reductase inhibitors, not only can improve the clinical efficacy of daunorubicin and other anthracycline anticancer drugs, but also can reduce the toxic side effects of daunorubicin.
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