9-AMINOACRIDINE 90-45-9 C13H10N2
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9-AMINOACRIDINE Basic information |
Product Name: | 9-AMINOACRIDINE |
Synonyms: | 9-acridinamine;9-amino-acridin;9-Aminoakridin;Acridin-9-amine;Acridine, 9-amino-;Aminacrin;Aminoacridine;Izoacridina |
CAS: | 90-45-9 |
MF: | C13H10N2 |
MW: | 194.23 |
EINECS: | 201-995-6 |
Product Categories: | Amines;Aromatics;Heterocycles |
Mol File: | 90-45-9.mol |
9-AMINOACRIDINE Chemical Properties |
Melting point | 238-240℃ |
Boiling point | 320.68°C (rough estimate) |
density | 1.268 |
refractive index | 1.5014 (estimate) |
storage temp. | Store below +30°C. |
solubility | ethanol: hazy |
pka | 9.99(at 20℃) |
λmax | 406nm(DMF)(lit.) |
Merck | 14,407 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 90-45-9(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | AR7300000 |
HazardClass | 6.1(b) |
PackingGroup | III |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
9-AMINOACRIDINE Usage And Synthesis |
Chemical Properties | yellow crystals or powder |
Uses | Acridine analog. DNA intercalating agent. |
Uses | antibacterial |
Definition | ChEBI: An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections |
General Description | Yellow needles. Free soluble in alcohol. |
Air & Water Reactions | Insoluble in water. |
Reactivity Profile | 9-AMINOACRIDINE is a moderately strong base. Neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides. |
Fire Hazard | Flash point data for 9-AMINOACRIDINE are not available; however, 9-AMINOACRIDINE is probably combustible. |
Purification Methods | It crystallises from EtOH or acetone and sublimes at 170-180o/0.04mm [Albert & Ritchie Org Synth Coll Vol III 53 1955, for hydrochloride, see below]. [Beilstein 22 H 463, 21 II 280, 21 III/IV 4174.] |
9-AMINOACRIDINE Preparation Products And Raw materials |
Raw materials | Phosphorus pentachloride-->Anthranilic acid-->9-Chloroacridine |
Preparation Products | Kallikrein |
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