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Probenecid with GMP Probenecid quality with GMP produce 57-66-9
Common name: Probenecid
Synonym: 4-(Dipropylsulfamoyl)benzoic acid
Chemical Name: 4-(Dipropylsulfamoyl)benzoic acid
Standard:USP35
CAS:57-66-9
Packing:25KG/Drum
Company name & address: Nanyang Tianhua Pharmaceutical Co., Ltd.
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Probenecid Basic information |
Anti-gout drug Indications Side effects Chemical Properties Uses Production methods |
Product Name: | Probenecid |
Synonyms: | 4-((dipropylamino)sulfonyl)-benzoicaci;4-(Dipropylsulfamoyl)benzoic acid;4-(dipropylsulfamoyl)benzoicacid;4-[(dipropylamino)sulfonyl]-benzoicaci;Apurina;benacen;Benemid;benemide |
CAS: | 57-66-9 |
MF: | C13H19NO4S |
MW: | 285.36 |
EINECS: | 200-344-3 |
Product Categories: | Miscellaneous;API;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API's;Vanilloid/TRPV channel;chemical additive;pharmaceutical intermediate;PROBENEMID;pharmaceutical chemicals;Pharmaceutical raw materials;anti-gout |
Mol File: | 57-66-9.mol |
produce 57-66-9 with GMP/quality with GMP |
Molecular formula: C13H19NO4S
Molecular weight: 285.36
Standard: USP35
[Appearance] white crystalline powder.
[Packing]:25KG/drum
[Valid period]24 months
[Storage]PRESERVED IN AN AIRTIGHT CONTAINER AND AVOID EXPOSURE TO HIGH TEMPERATURE.
PHYSICAL PROPERTY: WHITE CRYSTALLINE POWER, ODOURLESS, SLIGHTLY BITTER IN TASTE.
CHEMICAL PROPERTY: SOLUBLE IN ACETONE,SLIGHTLY SOLUBLE IN ALCOHOL OR CHLOROFORM,HARDLY SOLUBLE IN WATER,SOLUBLE IN DILUTE SODIUM HYDROXIDE SOLUTION,DARDLY SOLUBLE IN DILUTE ACID.
APPLICATION: MAINLY USED FOR SENSITIVE BACTERIA INFECTION, FOR ANTIGOUT DRUG.
Key control item:
MELTING POINT :198℃-200℃
PH (ACIDITY) : NMT 0.5 ML IS REQUIRED TO PRODUCE A PINK COLOR CONFIRMED
SELENIUM : ≤0.003%
LOSS ON DRYING :≤0.5%
RESIDUE ON IGNITION :≤0.1%
HEAVY METALS(PB) : ≤0.002%
ANY INDIVIDUAL IMPURITY:≤0.5%
TOTAL IMPURITY:≤2.0%
Uses produce 57-66-9 with GMP/quality with GMP
It is a kind of anti-gout drug. The product is organic acid, strongly fat-soluble, self-discharge from tubular secretion, very easily to be absorbed back. Therefore, in the presence of probenecid, the transfer of some organic acids in the tubular body will be inhibited, reducing the excretion of other organic acids. Thereby, it is used to treat chronic gout with being safe and effective. It has no effects on acute gout pain and inflammation and can’t be applied to acute gout.
It is used for the treatment of gout, rheumatoid arthritis and other chronic diseases.For the reduction of serum uric acid concentrations in chronic gouty arthritis and tophaceous gout in patients with frequent disabling gout attacks. Has also been effectively used to promote uric acid excretion in hyperuricemia secondary to the administra
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