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Thymopentin 69558-55-0 Thymopentin supplier
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Thymopentin is a five amino acid fragment of thymopoietin that exhibits immunostimulatory and anticancer activities. Thymopentin decreases iNOS activity in the treatment of Sezary Syndrome, a severe form of lymphoma. In leukemia cells, thymopentin inhibits proliferation and colony formation and induces differentiation. In macrophages, thymopentin increases pro-inflammatory cytokine secretion, activation of NF-κB, production of HSP72, and signaling by JNK. Thymopentin shows clinical benefit when used as an adjuvant, improving the response rate in subjects administered hepatitis B vaccines.
Cmmonly used as thymus pentapeptide injection, main treatment: can be used in patients with malignant tumors after radiotherapy and chemotherapy, immune function injury.
Items | Standard |
Characteristics
Specific rotation |
White or off-white powder -14°~22° |
Identification Biuret reaction IR HPLC |
Positive |
Clarity | Clear |
Alkalinity | 7.0~9.0 |
Water | ≤5.0% |
Amino acid composition | Conforms |
Related substances |
Single substance ≤1.5% Total substance ≤2.5% |
Endotoxin | ≤5Eu/mg |
Assay | 99.0%~101.0% |
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment.
Shipping :
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Items |
Specifications |
Appearance |
powder |
Purity (gc area %) |
≥ 98.0% |
H NMR |
Conforms to structure |
Product Description
Certification of Analysis
Items | Index | ||
Appearance | Colorless to light yellow transparent liquid | ||
Solid content % | 30.0 min | 50.0 min | 62.0-64.0 |
Free monomer (as AA) % | 0.50 max | 0.50 max | 1.0 max |
Density (20℃) g/cm3 | 1.10 min | 1.20 min | 1.20 min |
pH(1% water solution) | 2.5-4.5 | 2.5-4.5 | 2.0-3.0 |
Function&Application
PAA can be used as scale inhibitor and dispersant in circulating cool water systems in power plants, iron & steel factories, chemical fertilizer plants, refineries and air conditioning systems. Dosage should be in accordance with water quality and equipment materials. When used alone, 1-15mg/L is preferred.
Product Description
English name:2-Chloro-5-nitrobenzoic acid
Synonyms:5-nitro-2-chlorobenzoic acid; 2-chloro-5-nitrobenzoate
Molecular Formula:C7H3ClNO4
Molecular Weight:200.5566
CAS Registry Number:2516-96-3
EINECS:219-739-7
Melting point:164-168°C
Boiling point:356.5°C at 760 mmHg
Flash point:169.4°C
Vapour Pressur:1.06E-05mmHg at 25°C
Synonyms : RARECHEM AL BO 0234;2-CHLORO-5-NITROBENZOIC ACID;5-NITRO-2-CHLOROBENZOIC ACID;LABOTEST-BB LT00847209;2-chloro-5-nitro-benzoicaci;6-Chloro-3-nitrobenzoic acid;Benzoic acid, 2-chloro-5-nitro-;2-Chloro-5-nirtrobenzoic acid
Certification of Analysis
Item |
Specification |
Appearance |
light yellow crystalline powder |
Purity |
98.0% min |
Moisture |
0.5% max |
Residue on ignition |
0.1% max |
Heavy Metal |
≤20ppm |
Loss on drying |
5.0% max |
Function&Application
Used to synthesize 2-chloro-5-aminobenzoic acid, 5-nitrosalicylic acid, ester and amide intermediates.Used as intermediate of pesticide, medicine and organic pigment.
Product Description
English name: DL-Leucine
CAS No.:328-39-2
Formula: C6H13NO2
Molecular Weight: 131.17 .
Synonyms: Leucine, DL- (8CI);NSC 9252;2-Amino-4-methylvaleric acid;Pentanoic acid, 2-amino-4-methyl-;Valeric acid, 2-amino-4-methyl-;α-Aminoisocaproic acid;α-Amino-γ-methylvaleric acid;
EINECS: 206-328-2
Density: 1.036 g/cm3
Melting Point: 293-296 °C (subl.)(lit.)
Boiling Point: 225.772 °C at 760 mmHg
Flash Point: 90.344 °C
Solubility: soluble in water
Appearance: white crystalline powder
Loss on drying:≤0.2%
Heavy metal(bp):≤15ppm
Purity:≥99%
Application: Pharmaceutical Intermediates.
Certification of Analysis
Function&Application
Function
Supports extreme muscle growth
Builds strength and tremendous power
Timed release to support anti-catabolic effects
Support increased strength and mass
Support improved recovery and reduced soreness
Promote increased endurance exercise capacity
Provides support against catabolism.
Application
1. Skin Care: This product applied on the human skin is with the function of moisturizing, anti-wrinkle, adding nutrition,which is used fr the raw material of high quality mask, moisturizer and cleanser ,can also be used for shampoo and hair care products, bath liquid and so on.
2. Medicines and Health Products :
This product can improve body metabolism, immune function, inhibit cancer cells, activated cells.it has significant function in delaying the human aging, preventing osteoporosis.
3. Food: This product can be added to bread, cakes and various snacks, improve food nutrition structure, especially for children and the elderly digestion and absorption.
4. Dairy products: This product can be widely used in milk drinks, fresh milk, yogurt and other liquid dairy products .have the function of anti-whey precipitation, emulsion stability
5. Beverages:This product can be added to a variety of beverages to make high-energy drinks, play a complementary role in the supplemental energy and body building
Product Description
Product Name |
DL-2-Aminobutyric acid |
Synonyms |
DL-2-AMINO-N-BUTYRIC ACID; DL-ALPHA-AMINOBUTYRIC ACID |
CAS No |
2835-81-6 |
MDL number: |
MFCD00008093 |
EINECS number: |
220-616-5 |
MF |
C4H9NO2 |
MW |
103.12 |
Purity |
99%(min) |
Moisture |
0.5%(max) |
Chemical Properties: |
|
Appearence |
white to off-white powder |
mp |
291℃ |
Safety Information: |
|
Hazard Codes |
Xn: Harmful |
Risk Statements |
20/21/22-36/37/38 |
Safety Statements |
22-24/25-36-26 |
Usage: |
Pharmaceutical Intermediates |
Function&Application
DL-2-Aminobutyric acid is widely used in fields of medicine, food processing, industry, etc.
Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with side effects that included hair growth and reversal of male baldness.Since the 1990s, numerous generic forms of minoxidil have become available to treat hair loss while the oral form is still used to treat high blood pressure.
Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. It is available over the counter for treatment of androgenic alopecia, among other baldness treatments, but measurable changes disappear within months after discontinuation of treatment. Its effectiveness has largely been demonstrated in younger men (18 to 41 years of age), the younger the better.
Minoxidil is a potassium channel agonist. It contains the chemical structure of nitric oxide), a blood vessel dilator, and may be a nitric oxide agonist. This appears to explain its vasodilatory effects, but may also be linked to minoxidil’s ability to stimulate hair growth and treat hair loss. Since minoxidil is a nitric oxide-related compound, it was suspected to act via activation of guanylate cyclase, an enzyme involved in vasodilation.
COA OF Minoxidil
TEST ITEM |
SPECIFICATION |
RESULTS |
Appearance |
White to off-white crystal powder |
White arystal powder |
Identification |
Positive |
Positive |
Residue on ignition |
≤0.5% |
0.04% |
Heavy Metals |
≤20ppm |
4ppm |
Sulphated Ash |
≤0.1% |
0.04% |
Loss on drying |
≤0.5% |
0.12% |
Total impurities |
≤1.5% |
conforms |
Residual Solvents |
Methanol≤3000ppm Ethanol≤5000ppm Ethyl Acetate≤5000ppm |
conforms |
Assay(HPLC) |
97-103% |
99.53% |
Conclusion |
The report conforms to USP37 |
Product Description
Certification of Analysis
Item |
Specifications |
Results |
Appearance |
Yellow crystals |
Yellow crystals |
Content% ≥ |
99.00 |
99. 39 |
Water insolubles %≤ |
0.01 |
0.0037 |
Cl- % ≤ |
0. 2 |
0. 06 |
sulfate % ≤ |
0.3 |
0.10 |
As % ≤ |
0.0001 |
< 0.0001 |
Conclusion |
The results conforms with Enterprise standards |
Function&Application
Used in the manufacture of pigments, dyeing and oxidizing auxiliaries, paints, inks, red blood salt and potassium, explosives and chemical reagents, also used in steel heat treatment, stone printing, engraving and pharmaceutical industries.Its food additive grade product is mainly used as anti-caking agent of salt.
Product Description
Product Name Thymine
Synonyms 2,4(1H,3H)-Pyrimidinedione, 5-methyl-; 2,4-Dihydroxy-5-methylpyrimidine; 2,4-dioxy-5-methyl pyrimidine; 5-Methyluracil; Thy; 5-methyl-uracil; 5-methyl uracil; Thymine 2-4-Dihydroxy-5-methylpyrimidine; 5-methylpyrimidine-2,4(1H,3H)-dione
Molecular Formula C5H6N2O2
Molecular Weight 126.1133
CAS Registry Number 65-71-4
EINECS 200-616-1
Density 1.226g/cm3
Melting point 316-317°C
Boiling point 403.8°C at 760 mmHg
Refractive index 1.489
Flash point 198°C
Vapour Pressur 4.25E-07mmHg at 25°C
Certification of Analysis
Item |
Specification |
Specific rotation |
+39.5 to +41.5° |
State of solution(transmittance) |
Clear 98.0% min. |
Chloride[cl] |
0.020% max. |
Ammonium [NH4] |
0.02% max. |
Sulfate[SO4] |
0.020% max |
Iron[Fe] |
10ppm max. |
Heavy metals [Pb] |
10ppm max |
Arsenic[As2O3] |
1ppm max |
Other amino acids |
Chromatographically not detectable |
Loss on drying |
0.20% max. |
Residue on ignition[sulfated] |
0.10% max. |
Assay |
99.0% min |
Function&Application
It is a key intermediate for the synthesis of anti-aids drugs AZT, DDT and related drugs.
Product Description
CAS Number:16051-77-7
Name:D-Glucitol,1,4:3,6-dianhydro-, 5-nitrate
Superlist Name:Isosorbide 5-mononitrate
Formula:C6H9NO6
Molecular Weight:191.14 .
Synonyms:Glucitol,1,4:3,6-dianhydro-, 5-nitrate, D- (8CI);BM 22-145;ConpinRetardkaps;Corangin SR;Duride;Elantan;ElantanLong;Elantan Retard;IS 5MN;Imdur;Imdur Durules;Imtrate;Ismo;Isomonit;Isopen 20;Isosorbidemononitrate;Iturol;Momo Mack;Monis;Monit 20;Mono-Cedocard;Mono-Mack;Monocord 20;Monoket Retard;Monolong 40;Mononit;Monopront;Monosorb;Monosordil;Monovas;Ormox;Pentacard;Vasotrate;
EINECS:240-197-2
Density:1.56 g/cm3
Melting Point:88-93 °C
Boiling Point:364.5 °C at 760 mmHg
Flash Point:174.2 °C
Solubility:Soluble in water
Appearance:white to light yellow crystal powder
Certification of Analysis
Items |
Specifications |
Results |
Description |
A white powder |
White powder |
Identification |
a) IR: consistent with the spectrum obtained with that of its RS. b) HPLC: the retention time of the principle peak corresponds to that of its RS. c) TCL for lactose: position, color and size to the principal spot is consistent with that obtained with reference solution |
Conforms
Conforms
Conforms |
Nitrates |
NMT 0.5% |
Conforms |
Heavy metals |
NMT 10ppm |
Conforms |
Related substances |
Isosorbide: NMT 0.20% Isosorbide 2-nitrate: NMT 0.25% Isosorbide dinitrate: NMT 0.25% Any other single impurity (major): NMT 0.1% Total impurities: NMT 0.5% |
Conforms 0.023% 0.041% 0.0026% 0.067% |
Microbiological Quality |
Total aerobic microbial count: NMT 900cfu/g Total combined yeasts/Molds count: NMT 90 cfu/g Escherichia. Coli: absence |
<10cfu/g <10cfu/g absence |
Assay (Isosorbide Mononitrate) |
66.5%~73.5% |
68.5% |
Conclusion: conforms to the requirement of USP32 standard. |
Function&Application
Long-term treatment of coronary heart disease, prevention of vasospasm and mixed cardiomyopathy, is also applicable to the treatment after myocardial infarction and long-term treatment of chronic heart failure.
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