- Min.Order :1 Metric Ton
- Purity: 99.5%
- Payment Terms : L/C,T/T,
Keywords
AZASERINE 115-02-6 C5H7N3O4
Quick Details
- Appearance:Powder
- Application:115-02-6
- PackAge:Aluminium Foil Bag and Paper Drum
- ProductionCapacity:1|Metric Ton|Day
- Storage:1MT
- Transportation:By Sea/Air/DHL
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Details:
| AZASERINE Basic information |
| Product Name: | AZASERINE |
| Synonyms: | serine,diazoacetate(ester);AZASERINE;AZASERINE CRYSTALLINE;AZASERINE (50X) GAMMA-IRRADIATED CELLCUL TURE TESTE;ORTHO-DIAZOACETYL-L-SERINE;DIAZOACETYLSERINE;2-aMino-3-(2-diazoacetoxy)propanoic acid;O-DIAZOACETYL-L-SERINE |
| CAS: | 115-02-6 |
| MF: | C5H7N3O4 |
| MW: | 173.13 |
| EINECS: | 204-061-6 |
| Product Categories: | Antibiotics |
| Mol File: | 115-02-6.mol |
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| AZASERINE Chemical Properties |
| Melting point | 146-162° (dec) |
| alpha | D27.5 -0.5° (c = 8.46% in H2O at pH 5.18) |
| Boiling point | 303.75°C (rough estimate) |
| density | 1.5830 (rough estimate) |
| refractive index | 1.6190 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, yellow |
| pka | 8.55(at 25℃) |
| form | lyophilized powder |
| Merck | 13,902 |
| Safety Information |
| Hazard Codes | T |
| Risk Statements | 25-40 |
| Safety Statements | 53-36/37/39-45 |
| RIDADR | UN 3462 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | VT9625000 |
| F | 10 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 in mice, rats (mg/kg/day): 150, 170 orally (Sternberg, Philips) |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| AZASERINE Usage And Synthesis |
| Uses | antineoplastic, amino acid antagonist |
| Definition | ChEBI: A carboxylic ester resulting from the formal condensation of the carboxy group of diazoacetic acid with the alcoholic hydroxy group of L-serine. An antibiotic produced by a Streptomyces species. |
| Uses | Reagent used to induce pancreatic cancer in experimental animal models. |
| General Description | Pale yellow to green crystals. Used as an antifungal agent. |
| Air & Water Reactions | Very soluble in water. |
| Reactivity Profile | AZASERINE is incompatible with acids. |
| Purification Methods | Crystallise azaserine from 90% EtOH. Also dissolve it in H2O, filter it through Supercel and add EtOH to give azaserine as pale yellow crystals. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 1 pp 75-76 1961, Curphey & David J Org Chem 43 4666 1978, Beilstein 4 IV 3124.] |
| AZASERINE Preparation Products And Raw materials |
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