115-02-6 C5H7N3O4 ...

115-02-6 C5H7N3O4  AZASERINE

115-02-6 C5H7N3O4 AZASERINE

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AZASERINE 115-02-6 C5H7N3O4

Quick Details

  • Appearance:Powder
  • Application:115-02-6
  • PackAge:Aluminium Foil Bag and Paper Drum
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:1MT
  • Transportation:By Sea/Air/DHL

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Details:

 
AZASERINE Basic information
Product Name: AZASERINE
Synonyms: serine,diazoacetate(ester);AZASERINE;AZASERINE CRYSTALLINE;AZASERINE (50X) GAMMA-IRRADIATED CELLCUL TURE TESTE;ORTHO-DIAZOACETYL-L-SERINE;DIAZOACETYLSERINE;2-aMino-3-(2-diazoacetoxy)propanoic acid;O-DIAZOACETYL-L-SERINE
CAS: 115-02-6
MF: C5H7N3O4
MW: 173.13
EINECS: 204-061-6
Product Categories: Antibiotics
Mol File: 115-02-6.mol
AZASERINE Structure
 
AZASERINE Chemical Properties
Melting point  146-162° (dec)
alpha  D27.5 -0.5° (c = 8.46% in H2O at pH 5.18)
Boiling point  303.75°C (rough estimate)
density  1.5830 (rough estimate)
refractive index  1.6190 (estimate)
storage temp.  2-8°C
solubility  H2O: 50 mg/mL, clear, yellow
pka 8.55(at 25℃)
form  lyophilized powder
Merck  13,902
 
Safety Information
Hazard Codes  T
Risk Statements  25-40
Safety Statements  53-36/37/39-45
RIDADR  UN 3462 6.1/PG 3
WGK Germany  3
RTECS  VT9625000
10
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in mice, rats (mg/kg/day): 150, 170 orally (Sternberg, Philips)
MSDS Information
Provider Language
SigmaAldrich English
 
AZASERINE Usage And Synthesis
Uses antineoplastic, amino acid antagonist
Definition ChEBI: A carboxylic ester resulting from the formal condensation of the carboxy group of diazoacetic acid with the alcoholic hydroxy group of L-serine. An antibiotic produced by a Streptomyces species.
Uses Reagent used to induce pancreatic cancer in experimental animal models.
General Description Pale yellow to green crystals. Used as an antifungal agent.
Air & Water Reactions Very soluble in water.
Reactivity Profile AZASERINE is incompatible with acids.
Purification Methods Crystallise azaserine from 90% EtOH. Also dissolve it in H2O, filter it through Supercel and add EtOH to give azaserine as pale yellow crystals. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 1 pp 75-76 1961, Curphey & David J Org Chem 43 4666 1978, Beilstein 4 IV 3124.]
 
AZASERINE Preparation Products And Raw materials

 

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