PF-04691502 Basic information
Product Name: PF-04691502
Synonyms: PF-04691502;2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one;2-aMino-8-((1r,4r)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-Methoxypyridin-3-yl)-4-Methylpyrido[2,3-d]pyriMidin-7(8H)-one;PF-04691502 2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one;2-Amino-8-((1r,4r)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3;PF-04691502, 98%, a potent and selective inhibitor of PI3K and mTOR kinases
CAS: 1013101-36-4
MF: C22H27N5O4
MW: 425.48088
EINECS:
Product Categories: PI3K/Akt/mTOR;Inhibitors;Akt;mTOR;PI3K
Mol File: 1013101-36-4.mol
PF-04691502 Chemical Properties
density 1.36
Safety Information
MSDS Information
PF-04691502 Usage And Synthesis
Chemical Properties Pale Yellow Solid
Uses PF-04691502 is an potent and selective inihibitor of PI3K and mTOR Kinases with antitumor activity.
Uses PF-04691502 is an ATP-competitive PI3K/mTOR inhibitor with IC50 of 32 nM and also inhibits Akt T308/S473 with IC50 of 7.5 nM/3.8 nM.