Bosutinib Chemical Properties
Melting point 116-120 ºC
density 1.36
storage temp. room temp
solubility DMSO: ≥15mg/mL
color off-white to light brown
CAS DataBase Reference 380843-75-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
MSDS Information
Bosutinib Usage And Synthesis
Chemical Properties Pale Yellow Solid
Uses A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.
Uses peripheral vasolidator increases cerebral blood flow, potential therapeutic for Altzheimer’s disease, cognitive impairment and dementia
Uses Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively.
Definition ChEBI: An aminoquinoline that is 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline bearing additional cyano and methoxy substituents at positions 3 and 6 respectively.