- Min.Order :1 Kilogram
- Purity: 99%
- Payment Terms : L/C,T/T
Keywords
159351-69-6 Everolimus C53H83NO14
Quick Details
- Appearance:white powder
- Application:pharma
- PackAge:as clients needs
- ProductionCapacity:1|Metric Ton|Day
- Storage:RT
- Transportation:sea
Superiority:
Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:
1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
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2.Fast delivery
3.Better payment term
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Details:
Everolimus Chemical Properties
Melting point NA
Fp 2℃
storage temp. −20°C
Water Solubility Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.
Stability: Hygroscopic
Safety Information
Hazard Codes T,Xn,F
Risk Statements 48/25-36-20/21/22-11
Safety Statements 45-36/37-26-16
RIDADR UN 1648 3 / PGII
WGK Germany 2
F 10
MSDS Information
Everolimus Usage And Synthesis
Overview Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor[1-3]. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein[1]. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe)[4]. It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology[5, 6].
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