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Factory Supply High Purity 99% Pharmacy Material Gliclazide CAS 21187-98-4

Factory Supply High Purity 99% Pharmacy Material Gliclazide CAS 21187-98-4

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100 Gram

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  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : T/T,,MoneyGram

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21187-98-4 Gliclazide CAS 21187-98-4

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  • Appearance:Powder
  • Application:Used as a pharmaceutical intermediates.
  • PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
  • ProductionCapacity:20000|Kilogram|Day
  • Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
  • Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

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Factory Supply High Purity 99% Pharmacy Material Gliclazide CAS 21187-98-4


 
Gliclazide is an oral antihyperglycemic agent used for the treatment of diabetes mellitus type II. It belongs to the sulfonylurea class of insulin secretagogues, which stimulates β cells of the pancreas to release insulin. Gliclazide binds to the β cell sulfonyl urea receptor (SUR1), further blocking the ATP sensitive potassium channels. Therefore, the potassium efflux substantially decreases, causing depolarization of the β cells. Then the voltage-dependent calcium channels in the β cell are open, resulting in calmodulin activation, which in turn leads to exocytosis of insulin containing secretorty granules. Recent studies have also shown that gliclazide can effectiveimprove anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes and protect pancreatic beta-cells from damage by hydrogen peroxide.
 
 
Gliclazide Basic information
Description Hypoglycemic agents Pharmacological effects Pharmacokinetics Synthetic method Uses Side effects Contraindications Precautions Drug interactions References
Product Name: Gliclazide
Synonyms: )-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-(((hexahydrocyclopenta(c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n’-(3-azabicyclo(3.3.0)oct-3-yl)urea;s852;se1702
CAS: 21187-98-4
MF: C15H21N3O3S
MW: 323.41
EINECS: 244-260-5
Product Categories: Pharmaceutical;Active Pharmaceutical Ingredients;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Potassium channel;Aromatics;Sulfur & Selenium Compounds;Other APIs;Pharmaceutical intermediates;Anti diabetic
Mol File: 21187-98-4.mol
Gliclazide Structure
 
Gliclazide Chemical Properties
Melting point  163-169 °C(lit.)
density  1.2205 (rough estimate)
refractive index  1.6740 (estimate)
storage temp.  -20°C Freezer
solubility  methylene chloride: soluble
form  powder
color  white
Merck  14,4439
InChIKey BOVGTQGAOIONJV-UHFFFAOYSA-N
CAS DataBase Reference 21187-98-4(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  21-36/38-46-62-63
Safety Statements  25-26-36/37-53-24/25
RIDADR  3077
WGK Germany  2
RTECS  YT4500000
Toxicity LD50 orally in mice: >3 g/kg (Duhault)

 

Advantages:

 

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1.  Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2.  Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3.  Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to

insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4.  Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

 

Factory Supply High Purity 99% Pharmacy Material Gliclazide CAS 21187-98-4

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