5,6-DIAMINO-1,3-DIMETHYL URACIL Chemical Properties
Melting point 210-214 °C (dec.)(lit.)
Boiling point 243.6±50.0℃ (760 Torr)
density 1.350±0.06 g/cm3 (20 ºC 760 Torr)
Fp 101.1±30.1℃
Safety Information
WGK Germany 3
F 10-34
MSDS Information
5,6-DIAMINO-1,3-DIMETHYL URACIL Usage And Synthesis
Chemical Properties Pale Brown Solid
Uses Reactant involved in the synthesis of biologically active molecules including:• ;1H-Imidazol-1-yl substituted 8-phenylxanthines for use as adenosine receptor ligands1• ;Pyrimidinyl purinediones via cyclocondensation2• ;Theophylline derivatives as adenosine receptor antagonists3• ;Pteridine analogs for use as monoamine oxidase B and nitric oxide synthase inhibitors4• ;Fused tricyclic xanthines5• ;Cadmium uraciliminoethylpyridine complexes for use as antiproliferatives against C6 glioma cells6
Purification Methods It recrystallises from EtOH. The hydrochloride has m 310o (from MeOH), and the perchlorate has m 246-248o. [UV: Bredereck et al. Chem Ber 92 583 1959, Taylor et al. J Am Chem Soc 77 2243 1955, Beilstein 25 III/IV 4133.]
5,6-DIAMINO-1,3-DIMETHYL URACIL Preparation Products And Raw materials
Raw materials Cyanoacetic acid