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503612-47-3 Apixaban;BMS-562247 Top quality Apixaban 503612-47-3
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Product Name:Apixaban
Synonyms:Apixaban;Apixaban, BMS 562247-01;
CAS:503612-47-3
MF:C25H25N5O4
MW:459.504
density: 1.42
putity:99%min
The COA of this product :
ITEMS | SPECIFICATION | TESTRESULTS |
Appearance | Off-white or white powder | Conforms |
Identification | HPLC,NMR;LC-MS | Conforms |
Related substances | Individual impurity≤0.5% | 0.09% |
Total impurities≤1.0% | 0.20% | |
Loss on drying | ≤0.5% | 0.3% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤10ppm | Conforms |
Assay | ≥98.0 % | 99.1% |
Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM,
respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for
Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with the
concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),
modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highest
potency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.
4. Warm after-sale service Any of your question would be solved for the first as soon as possible.
Product Name:Apixaban CAS:503612-47-3
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