CasNo.41468-25-1,an enzyme prosthetic group Pyridoxal 5'-phosphateCAS:41468-25-1,(41468-25-1) Suppliers

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Keywords

41468-25-1 Pyridoxal 5'-phosphate DL-Tryptophan

Quick Details

Appearance:Yellow Crystalline Powder
Application: Pyridoxal 5-phosphate (PLP) (active form of Vitamin B6) is an enzyme prosthetic group that acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of do
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ProductionCapacity:1000|Metric Ton|Month
Storage: 2-8°C
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Details:

Introduction:

Product Name: Pyridoxal 5'-Phosphate

CAS No: 41468-25-1

EINECS No: 200-208-3

Molecular Formular: C8H12NO7P

Molecular Weight: 265.16

Appearance: Pale yellowish white crystalline powder

Pyridoxal-5’-phosphate monohydrate is a vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. It has the ability to inhibit purinergic receptors and intracellular influx of Ca2+. Pyridoxal-5’-phosphate monohydrate can modify peptides and suppress their precursor ionization efficiency. Research shows that pyridoxal-5'-phosphate-dependent enzymes can be inhibited by cycloserine.

Function：

Pyridoxal 5'-Phosphate as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.The aldehyde group of PLP forms a Schiff-base linkage (internal aldimine) with the ε-amino group of a specific lysine group of the aminotransferase enzyme. The α-amino group of the amino acid substrate displaces the ε-amino group of the active-site lysine residue in a process known as transaldimination. The resulting external aldimine can lose a proton, carbon dioxide, or an amino acid sidechain to become a quinoid intermediate, which in turn can act as a nucleophile in several reaction pathways.

Application：

1) Pyridoxal-5-Phosphate is used to treat Parkinson's disease

2) Promote the transaminase in transamination dopamine levels in the body

3) Used in the treatment of acute or chronic eczema dermatitis nettle examine pustular rash itching seborrheic eczema scaly rash drug eruption deficiency oral inflammation glossitis pregnancy reaction, asthma, etc

4) The main body of vitamin B6

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