High quality 864070-44-0 Empagliflozin in factory

Quack Detail for EMpagliflozin
 

Empagliflozin (trade name Jardiance) is really a drug from the gliflozin class, approved for that treatments for diabetes type 2 in adults in 2014. It turned out put together by Boehringer Ingelheim and Eli Lilly and Company.
Empagliflozin is an inhibitor with the sodium glucose co-transporter-2 (SGLT-2), and results in sugar in the blood being excreted by the kidneys and eliminated in urine.

About the Empagliflozin

Empagliflozin is really a selective inhibitor of SGLT-2 with IC50 value of 3.1 nM .
Sodium glucose cotransporter-2 (SGLT-2) is part of sodium glucose co-transporter family and plays a pivotal role in glucose reabsorption in the kidney .

Empagliflozin is a potent SGLT-2 inhibitor and it has a high amount of selectivity over SGLT-1, 4, 5 and 6 than other reported SGLT-2 inhibitors. When tested using a panel of human cell lines over-expressed SGLT-1, 2, 4, 5 and 6,

Empagliflozin treatment competitively bind to SGLT-2 over glucose at low dose . In human proximal tublular cell (PTC) cell line HK2 cells, Empagliflozin answer to 72 h inhibits the expression of SGLT-2 which reversed high glucose induced TLR4 expression, NF-κB binding, IL-6 secretion, AP-1 binding and CIV expression .

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Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
 
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
 
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