Everolimus Cas 1593...

Everolimus Cas 159351-69-6

Everolimus Cas 159351-69-6

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10 Gram

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  • Min.Order :10 Gram
  • Purity: 99%
  • Payment Terms : T/T,

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Top quality Everolimus Certica Cas 159351-69-6

Quick Details

  • Appearance:White Crystalline Powder
  • Application: It Can Be Used As Pharmaceutical Intermediates Etc.
  • PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
  • ProductionCapacity:1000|Metric Ton|Month
  • Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
  • Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

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Details:

 
 
Factory Make Cheap Price Everolimus CAS 159351-69-6
 
Product Name: Everolimus
Synonyms: 42-O-(2-Hydroxyethyl)-rapamycin;Certica;RAD-001;SDZRAD;Rapamycin, 42-O-(2-hydroxyethyl)-;Everolimus;Certican;CERTICAN(R)
CAS: 159351-69-6
MF: C53H83NO14
MW: 958.232
EINECS:  
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitor;Antineoplastic protein kinase inhibitors;mTOR inhibitor;Certican, Zortress, Afinitor;Anti-cancer&immunity;PI3K/Akt/mTOR
Mol File: 159351-69-6.mol
 
 
Everolimus Chemical Properties
mp  NA
storage temp.  −20°C
Stability: Hygroscopic
 
Safety Information
Hazard Codes  T
Risk Statements  48/25
Safety Statements  45
WGK Germany  2
F  10
 
MSDS Information
 
 
Everolimus Usage And Synthesis
Chemical Properties Off White Solid
Usage Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation
Usage Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM
Usage Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.
Usage Everolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a silyl-protected hydroxyethyl triflate moiety, followed by addition of an ethylhydroxy moiety to provide greater stability and bioavailability. Like all tacrolimus analogues, everolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Everolimus is extensively cited in the literature with over 2,000 citations.
 
Description
Everolimus  is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin 
It is currently used as an immunosuppressant to prevent rejection of organ transplants and treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.
Inhibition of mTOR, the molecular target of Everolimus, extends the lifespan of model organisms including mice, and mTOR inhibition has been suggested as an anti-aging therapy.

  

Advantages:
 
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
 
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
 
2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
 
3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.
 
4. Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

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