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CAS 5370-01-4 Mexiletine hydrochloride High Purity Mexiletine hcl
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High Purity Mexiletine hydrochloride 5370-01-4
Mexiletine hydrochloride Basic information |
Product Name: | Mexiletine hydrochloride |
Synonyms: | 1-(2,6-dimethylphenoxy)-2-aminopropanehydrochloride;1-(2,6-dimethylphenoxy)-2-propanaminhydrochloride;1-methyl-2-(2,6-xylyloxy)-ethylaminehydrochloride;1-methyl-2-(2,6-xylyloxy)-ethylaminhydrochloride;ko1173;koe1173hydrochloride;mexitil;MEXILETINE HYDROCHLORIDE |
CAS: | 5370-01-4 |
MF: | C11H18ClNO |
MW: | 215.72 |
EINECS: | 226-362-1 |
Product Categories: | Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Intermediates & Fine Chemicals;Pharmaceuticals;Amine Salts;Nitrogen Compounds;Organic Building Blocks;Amines;Heterocycles;TRILAFON;Cardiovascular APIs |
Mol File: | 5370-01-4.mol |
Mexiletine hydrochloride Chemical Properties |
Melting point | 200-203°C |
storage temp. | 2-8°C |
solubility | ethanol: 50 mg/mL |
pka | 9.0(at 25℃) |
form | powder |
color | white |
λmax | 272nm(MeOH)(lit.) |
Merck | 14,6169 |
CAS DataBase Reference | 5370-01-4(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38-22 |
Safety Statements | 36-26 |
WGK Germany | 3 |
RTECS | KR9300000 |
Toxicity | LD50 in male, female rats, mice, rabbits (mg/kg): 350, 400, 310, 400, 180, 160 orally; in male, female rats, mice (mg/kg): 27, 30, 43, 50 i.v. (Kast) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Mexiletine hydrochloride Usage And Synthesis |
Chemical Properties | White to Off-White Solid |
Uses | antipsychotic |
Uses | Antiarrhythmic (class IB) |
Definition | ChEBI: A hydrochloride composed of equimolar amounts of mexiletine and hydrogen chloride. |
Brand name | Mexitil (Boehringer Ingelheim). |
Biological Activity | Use-dependent sodium channel blocker (IC 50 values are 75.3 and 23.6 μ M for tonic and use-dependent block respectively). Class Ib antiarrhythmic, neuroprotective and antimyotonic agent. |
Mexiletine hydrochloride Preparation Products And Raw materials |
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