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Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | oral | > 1gm/kg (1000mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 1181, 1989. |
mouse | LD50 | intraperitoneal | 364mg/kg (364mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA |
New Cardiovascular Drugs. Vol. 5, Pg. 135, 1987. |
mouse | LD50 | intravenous | 27mg/kg (27mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: OTHER CHANGES |
New Cardiovascular Drugs. Vol. 5, Pg. 135, 1987. |
mouse | LDLo | oral | 8gm/kg (8000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BLOOD: CHANGES IN BONE MARROW NOT INCLUDED ABOVE |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 1181, 1989. |
rat | LD50 | intraperitoneal | 769mg/kg (769mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA |
New Cardiovascular Drugs. Vol. 5, Pg. 135, 1987. |
rat | LD50 | intravenous | 25mg/kg (25mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: OTHER CHANGES |
New Cardiovascular Drugs. Vol. 5, Pg. 135, 1987. |
rat | LDLo | oral | 8gm/kg (8000mg/kg) |
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH BLOOD: CHANGES IN BONE MARROW NOT INCLUDED ABOVE |
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