87239-81-4 C21H27N5...

87239-81-4 C21H27N5O9S2 Cefpodoxime proxetil
87239-81-4 C21H27N5O9S2 Cefpodoxime proxetil
87239-81-4 C21H27N5O9S2 Cefpodoxime proxetil
87239-81-4 C21H27N5O9S2 Cefpodoxime proxetil
87239-81-4 C21H27N5O9S2 Cefpodoxime proxetil

87239-81-4 C21H27N5O9S2 Cefpodoxime proxetil

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Cefpodoxime proxetil 87239-81-4 C21H27N5O9S2

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  • Appearance:white powder
  • Application:Organic Chemicals
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  • ProductionCapacity:|Metric Ton|Day
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Cefpodoxime proxetil Basic information
Brand Name(s) in US
Product Name: Cefpodoxime proxetil
Synonyms: (RS)-1(ISOPROPOXYCARBONYLOXY)ETHYL (+)-(6R,7R)-7-[2-(2-AMINO-4-THIAZOLYL)-2-[(Z)METHOXYIMINO]ACETAMIDO]-3-METHOXYMETHYL-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLATE;ORELOX;OTREON;U-76252;U-76253;VANTIN;(6r-(6-alpha,7-beta(z)))-bonyl)oxy)ethyleste;1-(((1-methylethoxy)car
CAS: 87239-81-4
MF: C21H27N5O9S2
MW: 557.6
EINECS: 1308068-626-2
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Metabolites & Impurities;Cefpodoxime
Mol File: 87239-81-4.mol
Cefpodoxime proxetil Structure
Cefpodoxime proxetil Chemical Properties
Melting point 111-113°C
RTECS XI0367370
storage temp. -20 C Freezer
solubility Soluble in DMSO
Sensitive Light Sensitive
CAS DataBase Reference 87239-81-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-42/43
Safety Statements 22-26-36/37/39
HS Code 30042000
Toxicity LD50 in male, female mice, male, female rats (mg/kg): >10000, >10000, >2000, >2000 s.c., 3502, 2535, >4000, >4000 i.p.; >8000, >8000, >4000, >4000 orally (Nakao, 1988)
MSDS Information
Cefpodoxime proxetil Usage And Synthesis
Brand Name(s) in US Simplicef (veterinary drug)
Vantin (human drug)
Chemical Properties Pale Yellow Solid
Uses A metabolite of Cefpodoxime Proxetil. An antibacterial.
Uses An antibacterial. A broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime
Definition ChEBI: The 1-[(isopropoxycarbonyl)oxy]ethyl (proxetil) ester prodrug of cefpodoxime. After swallowing, hydrolysis of the ester group occurs in the intestinal epithelium, to release active cefpodoxime in the bloodstream. It is used to treat acute otitis media, pha yngitis, and sinusitis.
Brand name Vantin (Pharmacia & Upjohn).
Cefpodoxime proxetil Preparation Products And Raw materials
Raw materials Ethyl acetate-->Dichloromethane-->Magnesium sulfate-->Benzoyl peroxide-->Sulfuryl chloride-->Ethyl chloroformate-->Potassium bisulfate -->18-Crown-6 -->Calcium chloride dihydrate-->1-Chloroethyl chloroformate-->1-Iodoethyl isopropyl carbonate-->1-Chloroethyl isopropyl carbonate
 
 
 
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