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1400-61-9 Nystatin 99% High Purity CAS No. 1400-61-9
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Introduction :
Product name: Nystatin
CAS No.: 1400-61-9
MF: C47H75NO17
EINECS No.: 215-749-0
Purity:98%
MW:276.4137
Usage: Antibiotic and Antimicrobial Agents
Specification :
Test items |
Standard |
Result |
|
Description |
Yellow brown powder |
Conforms |
|
Identification |
IR |
IR spectrum of sample is the same as working standard |
Conforms |
HPLC |
HPLC RT of the sample is the same as the working standard |
Conforms |
|
Melting point |
165.0°C~169.0°C |
165.8°C~167.0°C |
|
Optical rotation |
-23°~-29° |
-27.4° |
|
Loss on drying |
NMT 1.0 % |
0.17% |
|
Residue on ignition |
NMT 0.1 % |
0.03% |
|
Heavy metals |
NMT 20ppm |
Conforms |
|
Related substances |
|||
Impurity A |
NMT 0.1 % |
Not detected |
|
Impurity B |
NMT 0.1 % |
Not detected |
|
Impurity C |
NMT 0.1 % |
0.02% |
|
Single impurity |
NMT 0.2 % |
0.17% |
|
Total impurity |
NMT 1.0 % |
0.60% |
|
Assay |
NLT 99.0% |
99.0% |
Function:
1. Nystatin is often used as prophylaxis in patients who are at risk for fungal infections, such as AIDS patients with a low CD4+ count and patients receiving chemotherapy.
2. It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the gut, it is safe for oral use and does not have problems of drug interactions.
3. It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.
4. In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art. For example, it was applied to wood panel paintings damaged as a result of the Arno River Flood of 1966 in Florence, Italy.
Nystatin is also used as a tool by scientists performing "perforated" patch-clamp electrophysiologic recordings of cells. When loaded in the recording pipette, it allows for measurement of electrical currents without washing out the intracellular contents, because it forms pores in the cell membrane that are permeable to only monovalent ions.
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
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High Quality Nystatin Powder Purity 99% CAS 1400-61-9 Best Price
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