Non-peptide selecti...

Non-peptide selective antidiuretic hormone receptor antagonist Tolvaptan CAS:150683-30-0
Non-peptide selective antidiuretic hormone receptor antagonist Tolvaptan CAS:150683-30-0
Non-peptide selective antidiuretic hormone receptor antagonist Tolvaptan CAS:150683-30-0
Non-peptide selective antidiuretic hormone receptor antagonist Tolvaptan CAS:150683-30-0
Non-peptide selective antidiuretic hormone receptor antagonist Tolvaptan CAS:150683-30-0

Non-peptide selective antidiuretic hormone receptor antagonist Tolvaptan CAS:150683-30-0

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50 Gram

FOB Price:USD 576.0000 -630.0000
  • Min.Order :50 Gram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram

Keywords

150683-30-0 Tolvaptan EINECS: 1308068-626-2

Quick Details

  • Appearance:Off-White Solid
  • Application: Tolvaptan (OPC-41061) is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. Tolvaptan (OPC-41061) is u
  • PackAge: according to customers' requirements
  • ProductionCapacity:10000|Metric Ton|Month
  • Storage:Refrigerator
  • Transportation:according to customers' requirements

Superiority:

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present, our customers have spread all over the world, we have rich Transportation experience, we aim to serve customers, to help customers, solve problems for customers. Look forward to working with you!
 

Details:

Introduction:
Product name:Tolvaptan
CAS NO.:150683-30-0
Synonyms:Tolvaptan
Category:Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Purity:99% Tolvaptan
Appearance:Tolvaptan powder
Shelf life:2 years for Tolvaptan
Function:
1. Tolvaptan is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia. Upon oral administration, tolvaptan selectively and competitively binds to and blocks the V2 receptor located in the walls of the vasculature and luminal membranes of renal collecting ducts, thereby preventing the binding of vasopressin to the V2 receptor. This prevents water absorption in the kidneys and increases the excretion of electrolyte-free water via the kidneys. This reduces intravascular volume and increases serum sodium concentrations and osmolality.
2. Tolvaptan is a vasopressin 2 receptor antagonist which is used for short term treatment of severe hyponatremia in patients with heart failure, cirrhosis or syndrome of inappropriate secretion of antidiuretic hormone (SIADH). It has been used experimentally to prevention progression of disease in autosomal dominant polycystic kidney disease (ADPKD). Tolvaptan recently has been implicated in causing serum aminotransferase elevations as well as clinically apprent acute liver injury during long term use.

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All Key Manufacturers and Suppliers of Baoji Guokang have routine inspections to ensure they are in compliance with the standards set in place during the original Supplier Assessment Inspection.
 
Production Inspection Process:
Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.
- Raw material before any production begins
- Pre-production samples to ensure specifications are being met
- In-process to confirm that standards are maintained
- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged
correctly to prevent any damage in transit.
We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.
We will arrange the subsequent shipments from our factory to your warehouse.
We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

  We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.
   Delivery can be offered.
    - Utilizing your own freight-forwarder
    - FOB to a port in China
    - CIF to a port near you
   Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.
1.Client is first.We are trying to bring maximum profit to our clients and we only share small.
2.Credibility is the most important.
3.Quality control is our life.
4.Great sense of responsibility.
We will be responsible for not only our products, our clients, our suppliers, also the society.

 

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