16 A Hydroxpredniso...

16 A Hydroxprednisolone

16 A Hydroxprednisolone

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1 Metric Ton

Negotiable

  • Min.Order :1 Metric Ton
  • Purity: 99%
  • Payment Terms : T/T,

Keywords

11a,16b,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione 11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 11β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione

Quick Details

  • Appearance:white power
  • Application:Pharma;Industry;Agricultural;chemical reaserch
  • PackAge:as your requirement
  • ProductionCapacity:1000|Metric Ton|Month
  • Storage:Keep it in dry,shady and cool place
  • Transportation:SEA OR AIR

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Details:

16a-hydroxyprednisolone, an intermediate of glucocorticoid API, is a synthetic intermediate of triamcinolone triamcinolone, budesonide, cycsolonide and desonide that has been approved for market. As an inhaled glucocorticoid, Ned drugs are characterized by local medication, low dose, strong local anti-inflammatory effect and small systemic side effects, and are widely used in the treatment of refractory asthma and inflammation.
 
Prednisolone is a synthetic glucocorticoid with a similar effect to prednisolone. It has anti-inflammatory and anti-allergic effects, with strong anti-inflammatory effect and weak water and salt metabolism. This product is hydroxyl compound (hydroxyl at the 11th position), which has good effect in local application and is also suitable for patients with liver insufficiency. Oral absorption is rapid and complete, reaching the peak blood drug concentration within 1 hour, plasma protein binding rate of 90% ~ 95%, and half-life of about 200 minutes. Can enter fetal circulation, appear in the milk dosage is 0.07% ~ 0.23%. Via liver inside metabolization, basically be excreted from kidney, among them primitive medicine occupies 20% above. It is suitable for treating allergic diseases such as eczema and dermatitis, connective tissue diseases such as lupus erythematosus and dermatomyositis.

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