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Dithranol high quality Dithranol Dithranol
CAS Number: 1143-38-0 Name: 1,8-Dihydroxy-anthrone Superlist Name: Dithranol Molecular Structure: Molecular Structure of 1143-38-0 (1,8-Dihydroxy-an…
Dithranol API
CAS NO: 1143-38-0
BP/EP/USP
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Dithranol is a Hydroxyanthrone, anthracene derivative, medicine applied to the skin of people with psoriasis. It is available as creams, ointment or pastes in 0.1 to 2% strengths. The terms dithranol and anthralin are sometimes used synonymously.
Dithranol API
CAS NO: 1143-38-0
BP/EP/USP
High quality & Good price
Reliable Dithranol supplier
Product Name: Anthralin
CAS Number: 1143-38-0
Specification: 99% min
Appearance : White or almost white crystalline powder
Anthalin accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. In addition Dithranol may act by reducing the elevated levels of cGMP that occurs in psoriasis.
Anthralin is a synthetic compound whose precise mechanism of anti-psoriatic action is not yet fully understood. However, numerous studies have demonstrated anti-proliferative and anti-inflammatory effects of anthralin on psoriatic and normal skin. The anti-proliferative effects of anthralin appear to result from both an inhibition of DNA synthesis as well as from its strong reducing properties.
Recently, anthralin’s effectiveness as an anti-psoriatic agent has also been in part attributed to its abilities to induce lipid peroxidation and reduce levels of endothelial adhesion molecules which are markedly elevated in psoriatic patients. Unlike retinoids and PUVA, anthralin does not inhibit liver microsomal enzyme activity; consequently, the likelihood of adverse drug interactions is greatly reduced when other agents are administered concomitantly with anthralin.
side effects
It temporarily stains the skin a yellowy-brown and permanently stains clothing fabrics. It may cause a local burning sensation and irritation; this may be minimised by careful attention to the details of treatment and only gradually stepping up through the strengths of dithranol formulations. The surrounding skin can be protected using soft white paraffin and the treated area is covered with tube gauze.
Packaging
[Storage] Stored in a clean, cool and dry area; keep away from strong, direct light.
[Shelf Life] 2 years when properly stored.
[Packing]
Inner double plastic bags--25kg/Fiber drum (35*35*53cm, GW: 28kg, NW: 25kg, 0.06CBM);
Inner double plastic bags--5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg);
Inner double plastic bags--1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
[Delivery] 5 working days after payment.
About our company
Founded in 2014, as a professional international pharmaceutical corporation,
headquartered in Xi'an (China), KonoChemCo., Ltd. is a leading producer of
standardized herbal extracts, natural active ingredients and APIs for pharmaceutical,
health food and cosmetic industries.
Bulk Herbal Nutrients& Phytochemical Manufacture, Food Ingredients Supplier
The Most Favorable Price Best Quality
Please visit our website: www.konochemical.com
Contact us via Email: sales4@konochemical .com
5. Package of our products
6.Extraction equipment
To know more about our products, please check the catalogue at below:
PRODUCTS CATALOGUE OF KONO CHEM |
|||||
NO |
NAME |
SOURCE |
PURITY |
STANDARD |
PACKAGE |
001 |
Coenzyme Q10 |
Tobacco |
10%-99% |
USP32 |
Drum & Bag |
002 |
L-Glutathione |
Yeast |
99% |
JP |
Drum & Bag |
003 |
Ecdysterone |
cyanotis arachnoidea |
50%-98% |
CP2005 |
Drum & Bag |
004 |
Capsaicin |
Chili pepper |
10%-95% |
USP32 |
Drum & Bag |
005 006 |
Matrine Oxymatrine |
Sophora flavescens Sophora flavescens |
1%-98% 1%-98% |
USP32 USP32 |
Drum & Bag Drum & Bag |
007 |
Raspberry Ketone |
Raspberry |
99% |
USP32 |
Drum & Bag |
008 |
Oleanolic Acid |
ligustrum lucidum ait. |
98% |
CP2010 |
Drum & Bag |
009 |
Ursolic Acid |
Eriobotrya japonica(Thunb.)Lindl |
1%-98% |
CP2010 |
Drum & Bag |
010 |
Chlorogenic Acid |
Eucommia ulmoides Oliv. |
1%-98% |
CP2010 |
Drum & Bag |
011 |
Usnic Acid |
Usneaceae |
98% |
CP2010 |
Drum & Bag |
012 |
Shikimic Acid |
Illicium verum Hook.f.) |
98% |
USP32 |
Drum & Bag |
013 |
Sinomenine Hcl |
Sinomenium actum Rehd.et |
98% |
USP32 |
Drum & Bag |
014 |
Berberine Hcl |
Coptis chinensis Franch |
98% |
CP2010 |
Drum & Bag |
015 016 |
Silymarin Silybinin |
Milk thistle Milk thistle |
80% 98% |
EP6 EP6 |
Drum & Bag Drum & Bag |
017 018 019 020 021 022 023 |
Lutein Zeaxanthin Lycopene Beta carotene Canthaxanthin Fucoxanthin Astaxanthin |
Marigold flower Marigold flower Tomato Carrot Algae Brown algae Haematococcus pluvialis |
2%-98% 5%-20% 1%-10% 1%-98% 1%-10% 1%-10% 1%-10% |
USP32 IN HOUSE USP32 USP32 USP32 IN HOUSE IN HOUSE |
Drum & Bag Drum & Bag Drum & Bag Drum & Bag Drum & Bag Drum & Bag Drum & Bag |
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