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Arecoline hydrobromide 300-08-3 pyridine derivative
Superiority
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Company information
Founded in 2012 as a professional international pharmaceutical corporation, headquartered in Xi'an (China), Xi'an Konochemical Co., Ltd, is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.
Annually, more than 3,000 tons of a wide range of herbal extracts and natural active substances are extracted at Xi'an Konochemical Co.,Ltd manufacturing plant near Xi'an, China. These extracts are in compliance with worldwide GMP norms, international Pharmacopoeias, and international regulations.
The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Konochemical. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.
Basic Introduction
Product name: Arecoline Hydrobromide
CAS No.: 300-08-3
Assay: HPLC/ESI-MS
Molecular formula : C8H13NO2.HBr
Molecular weight : 236.11
Appearance: White fine powder
Description
Arecoline is a natural alkaloid that is found in the betel nut of the Areca palm. It is an agonist of the muscarinic acetylcholine receptors with EC50 values of 7, 95, 11, 410, and 69 nM for M1, M2, M3, M4, and M5, respectively. Generally, arecoline causes smooth muscle contraction. Arecoline and other muscarinic receptor agonists have been shown to improve learning and memory and may prove to be useful in treating dementia.
Function
(1)It has the heart stimulating effectarecoline hydrobromide.
(2)Anti-cancer and anti inflammatoryarecoline hydrobromide.
(3)It can be used to local anesthesia, refrigeration, anti-inflammation and detumescencearecoline hydrobromide.
(4)It used in sweating profusely with body temperature dropping; muscle spasm in choleraarecoline hydrobromide.
(5)It used in the treatment of rheumatism, intermittent fevers and acute inflammatory infectionsarecoline hydrobromide.
Application
Owing to its muscarinic and nicotinic agonist properties, arecoline has shown improvement in the learning ability of healthy volunteers. Since one of the hallmarks of Alzheimer's disease is a cognitive decline, arecoline was suggested as a treatment to slow down this process and arecoline administered intravenously did indeed show modest verbal and spatial memory improvement in Alzheimer's patients, though due to arecoline's possible carcinogenic properties,it is not the first drug of choice for this degenerative disease.
Arecoline has also been used medicinally as an antihelmintic (a drug against parasitic worms).
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
Blue plastic drum / Galvanized steel drums/ 200kg Iron drum or 25kg plastic bucket
Founded in 2012 as a professional international pharmaceutical corporation, headquartered in Xi'an (China), Xi'an Konochemical Co., Ltd, is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.
Annually, more than 3,000 tons of a wide range of herbal extracts and natural active substances are extracted at Xi'an Konochemical Co.,Ltd manufacturing plant near Xi'an, China. These extracts are in compliance with worldwide GMP norms, international Pharmacopoeias, and international regulations.
The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Konochemical. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.
Kono Chem is headquarted in Xi’ an Shaanxi Province, China, with convenient transportation access, covering an area of 312, 000 square meters, and technicians accounted for 35% of the total employees. Presently, we have two chemical fermentation plant, one test reaction plant, and one Provincial Research and Development Center now. Our well-equipped facilities and excellent quality control throughout production enables us to guarantee customer satisfaction. We insist in innovation and produce high quality products. And our workshops are GMP standard.
We also have strong professional research and development team, talented personnel and completely equipped laboratory for the quality controlling. Various Detection Devices are equipped, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
From the very beginning, we strictly manage our production according to the international standard like ISO9000,ISO14001, now has received the recogonition from costomers all over the world and has passed the audit by authoritative labs. At present, our products are mainly related to Biopharmaceuticals, Health Care Products, Cosmetic Ingredients, APIs, Intermediates, as well as some custom synthesis products.
Thanks to our EHS management system and high quality control, now 85% of our products are well-selling and appreciated in almost 50 countries all over the world, and established long-term cooperative business relationship with multinational companies such as CIPLA,BIOCON,DSM.
Icy Liu
Tel: +86 29 88770941
Phone:18092125754
Fax:+86 29 81330164
Email: sales7@konochemical .com
Web: www.konochemical.com
Address :11 Daqing Road, Xi’an,Shaanxi 710082, P.R China
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