Podophylline is derived from the roots of podophyllum plant. Podophylline is applied directly to genital warts. When podophylline penetrates the wart tissue, it has a toxic effect on the nuclei of the wart cells.
The nucleus is the cell's control centre. Podophylline controls cell division and multiplication (mitosis). This results in the healthy growth of tissue.
Podophylline is an antimitotic and by its action on the nuclei, prevents the wart cells from dividing. This stops the cells multiplying. Over time, all the wart cells die and new healthy tissue grows in their place.
-Podophylline is mainly used in treat acuity condyloma.
-Podophylline has the effect in relieving rheumatism, prevent cough and ache, invigorate the circulation of blood and detoxification.
-As Antiviral agents and antineoplastic drugs. Podophylline can solve hot, diminish inflammation, ease pain, broken blood, efficiency promoting tissue regeneration.
-Podophyllum extract displays a range of activities such as cathartic, purgative, antiviral, vesicant, and antihelminthic.
-Additionally, the lignan and its derivatives are exciting leads for anti-tumor agent. For instance, podophyllum extract is the pharmacological precursor for the important anticancer drug etoposide.
-Podophyllum extract is also used as a gel or solution to treat genital warts with noticeably shorter duration and fewer side effects.