96036-03-2 Mepem Mepem Price
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Meropenem is a β-lactam antibiotic of the carbapenem subclass that has been shown to inhibit penicillinase-negative, -positive and methicillin-susceptible staphylococci. This compound demonstrates the ability to also affect strains of 11 species of streptococci. Mechanistic studies suggest that Meropenem's antimicrobial activity is based on its high affinity for the majority of penicillin-binding proteins, which are cell wall-synthesizing enzymes. Meropenem is very effective because it resists inactivation by the majority of microbial LACTB (β-lactamases) as well as kidney dehydropeptidase I. Experiments have shown Meropenem to have a low toxicity profile and, in contrast to similar compounds, no central nervous system toxicity.
Name |
Meropenem |
Synonyms |
(4R,5S,6S)-3-[[(3S,5S)-5-Dimethylcarbamoylpyrrolidin-3- |
Brand |
Salus |
Molecular Formula |
C17H25N3O5S |
Molecular Weight |
383.46 |
CAS Registry Number |
96036-03-2 |
Items |
Specification |
|
Appearance |
White or off-white powder |
|
Identification |
Meets the requirements |
|
pH |
7.3-8.3 |
|
Loss on drying |
9.0%~12.0% |
|
Chromatographic |
RRT(0.45) |
0.80% MAX |
purity |
RRT(1.90) |
0.60% MAX |
Particulate matter |
≥10 um |
≤6000 pc/g |
≥25 um |
≤600 pc/g |
|
Uniformity of dosage unites |
Meets the requirements |
|
Bacterial endotoxinsunder |
≤0.125EU/mg |
|
Sterility |
Meets the requirements |
|
Content of sodium |
5.3%-8.0% |
|
Assay(C17H25N3O5S) on anhydrous basis |
≥ 76.0% |
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