- Min.Order :1 Kilogram
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,
Keywords
Misoprostol 59122-46-2 Misoprostol 59122-46-2
Quick Details
- Appearance: White powder
- Application:Used
- PackAge:sample package
- ProductionCapacity:1000|Kilogram|Week
- Storage:dry and cool
- Transportation:By air
Superiority:
1.Reasonable price:
We provide high quality products with competitive price in china,
2.Low moq:
No worry about the low moq, our moq is 1 gram or lower.
3.Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.
4.Super-good quality
We have strict quality control system .Good reputation in Market
Contact us
If you have any further questions or need a sample,Please do not hesitate to contact us.
Leah| Senior Sales | Qingdao Sigmachemical Co.,Ltd
| Address:No 70,Shandong Road,Qingdao city,China
Details:
Specifciation:
1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory
Product Description
misoprostol, sold under the brandname cytotec among others, is a medication used to start labor, cause an abortion, prevent and treat stomach ulcers, and treat postpartum bleeding due to poor contraction of the uterus.for abortions it is often used with mifepristone or methotrexate.by itself effectiveness for this purpose is between 66% and 90%.it is taken either by mouth, under the tongue, or placed in the vagina.
common side effects include diarrhea and abdominal pain. it is pregnancy category x meaning that it is known to result in negative outcomes for the baby if taken during pregnancy. uterine rupture may occur. it is a prostaglandin analogue — specifically, a synthetic prostaglandin e1 (pge1).
misoprostol was developed in 1973.it is on the world health organization's list of essential medicines, the most effective and safe medicines needed in a health system.it is available as a generic medication.the wholesale cost in the developing world is about 0.36 to 2.00 usd a dose.a months supply to treat stomach ulcers in the united states is between 100 and 200 usd.the same costs between 30 and 55 eur in europe.
Function&Application
misoprostol is used for the prevention of nsaid-induced gastric ulcers. it acts upon gastric parietal cells, inhibiting the secretion of gastric acid by g-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic amp levels and decreased proton pump activity at the apical surface of the parietal cell. because other classes of drugs, especially h2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking nsaids and are at high risk for nsaid-induced ulcers, including the elderly and people with ulcer complications. misoprostol is sometimes coprescribed with nsaids to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in arthrotec).
misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. for instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. however, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
however, even in the treatment of nsaid-induced ulcers, omeprazole proved to be at least as effective as misoprostol,[10] but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.
specification
| item | standard | test results | |
|
identification |
a.h-nmr:comply with the structure |
complies |
|
|
b.lc-ms:comply with the structure |
complies |
||
|
c.the ir spectrum of sample should be identical with that of reference standard; |
complies |
||
|
d.hplc-esi-ms the retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay. |
complies |
||
|
crystallinity |
meets the requirements. |
complies |
|
|
loss on drying |
≤2.0% |
0.19% |
|
|
heavy metals |
≤10 ppm |
<10ppm |
|
|
water |
≤1.0% |
0.1% |
|
|
sulphated ash |
≤0.5%, determined on 1.0 g. |
0.009% |
|
|
related substances |
unspecified impurities: for each impurity |
≤0.10% |
<0.10% |
|
total impurity |
≤0.5% |
0.18% |
|
|
purity |
≥99.0% |
99.7% |
|
|
assay |
99.0%~101.0% (anhydrous substance). |
99.8% |
|
|
microbiological analysis |
|||
|
total plate count |
≤1000cfu/g |
complies |
|
|
yeast and moulds |
≤100cfu/g |
complies |
|
|
e. coli. |
absent |
negative |
|
|
salmonella |
absent |
negative |
|
|
s.aureus |
absent |
negative |
|
|
storage |
preserve in well-closed, light-resistant and airtight containers. |
complies |
|
2.Fast Delivery Within 3 days
3.SGS,BV,GMP,ISO approve
4.Professional factor
The aim of Sigma is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Sigma has become the "Top 500 Chinese manufactur
Our Services
FAQ
Q1: Are you a manufacturer
Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us
Click the lookchem"Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept
For small order,you can pay by T/T, or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price
Surely,It depend on your qty
Q5:How can i get a sample
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
If you are interested,welcome to contact with us.
Pls send message if you are interested,click "send" as below ^.^
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