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Axitinib Axitinib 319460-85-0
Product name: Axitinib
Cas Number: 319460-85-0
Moculer formula:C22H18N4OS
Moculer weight: 386.47
Molar mass: 386.469 g/mol
Appearance: Off-white powder
Assay(By HPLC): ≥99.0%
Axitinib is a small molecule tyrosine kinase inhibitor developed by Pfizer. It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models and has shown partial responses in clinical trials with renal cell carcinoma (RCC) and several other tumour types.
Diarrhea, hypertension, fatigue, decreased appetite, nausea, dysphonia, hand-foot syndrome, weight decreased, vomiting, asthenia, and constipation are the most common side effects occurring in more than 20% of patients
Item |
Specification |
Result |
Appearance |
White Powder or Crysta Powder |
Conforms |
Mesh Size |
100% through 80% mesh size |
Conforms |
Identification |
Identical to R.S. sample |
Conforms |
Assay |
99% min |
Conforms |
Loss on Drying |
≤5.0% |
3.11% |
Ash |
≤5.0% |
Conforms |
Heavy metals |
≤10.0mg/kg |
Conforms |
Arsenic(As) |
≤2.0mg/kg |
Conforms |
Cadmium(Cd) |
≤1.0mg/kg |
Conforms |
Mercury(Hg) |
≤0.1mg/kg |
Conforms |
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