CasNo.918504-65-1,Vemurafenib,(918504-65-1) Suppliers

0 Metric Ton	Negotiable

Min.Order :0 Metric Ton
Purity: 98% min

Keywords

Vemurafenib PLX-4032; RG7204; R7204; RO5185426; PLX4032 918504-65-1

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Application:
PackAge:10mg;50mg;100mg
ProductionCapacity:50-100|Metric Ton|Day
Storage:-20℃
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Vemurafenib (PLX4032, RG7204; RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.
IC50 value: 31 nM(B-RafV600E); 48 nM (c-Raf )[1]
Target: B-RafV600E
Target: PLX4032 inhibits B-RAFV600E, C-RAF, as well as wildtype B-RAF, with IC50 of 31 nM, 48 nM and 100 nM, respectively. PLX4032 also inhibits several non-RAF kinases, including ACK1, KHS1, and SRMS, with IC50 of 18 nM to 51 nM [1].

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Details:

Vemurafenib (PLX4032, RG7204; RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.
IC50 value: 31 nM(B-RafV600E); 48 nM (c-Raf )[1]
Target: B-RafV600E
Target: PLX4032 inhibits B-RAFV600E, C-RAF, as well as wildtype B-RAF, with IC50 of 31 nM, 48 nM and 100 nM, respectively. PLX4032 also inhibits several non-RAF kinases, including ACK1, KHS1, and SRMS, with IC50 of 18 nM to 51 nM [1].

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