5-Fluorouracil

5-Fluorouracil

5-Fluorouracil

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0 Metric Ton

Negotiable

  • Min.Order :0 Metric Ton
  • Purity: 98% min

Keywords

5-Fluorouracil 5-FU 51-21-8

Quick Details

  • Appearance:
  • Application:
  • PackAge:200mg
  • ProductionCapacity:50-100|Metric Ton|Day
  • Storage:-20℃
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Superiority:

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.
IC50 value:
Target: Nucleoside antimetabolite/analog
5-Fluorouracil is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-Fluorouracil leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.

 

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Details:

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.
IC50 value:
Target: Nucleoside antimetabolite/analog
5-Fluorouracil is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-Fluorouracil leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.

 

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