MG-132 MG132; MG 132 133407-82-6
MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.
IC50 value: 100 nM( proteasome); 1.2 uM(calpain) [1]
Target: proteasome
in vitro: MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM.
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MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.
IC50 value: 100 nM( proteasome); 1.2 uM(calpain) [1]
Target: proteasome
in vitro: MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM.
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