CasNo.1187594-09-7,Baricitinib,(1187594-09-7) Suppliers

0 Metric Ton	Negotiable

Min.Order :0 Metric Ton
Purity: 98% min

Keywords

Baricitinib INCB 028050; LY 3009104; INCB028050; LY3009104; LY-3009104; INCB-028050 1187594-09-7

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PackAge:10mg;50mg;100mg
ProductionCapacity:50-100|Metric Ton|Day
Storage:-20℃
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Baricitinib(INCB 028050; LY 3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.
IC50 Value: JAK1 (5.9 nM) and JAK2 (5.7 nM) [1].
Target: JAK1/2
in vitro: INCB028050 inhibits intracellular signaling of multiple proinflammatory cytokines including IL-6 and IL-23 at concentrations <50 nM. Significant efficacy

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Details:

Baricitinib(INCB 028050; LY 3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.
IC50 Value: JAK1 (5.9 nM) and JAK2 (5.7 nM) [1].
Target: JAK1/2
in vitro: INCB028050 inhibits intracellular signaling of multiple proinflammatory cytokines including IL-6 and IL-23 at concentrations <50 nM. Significant efficacy

url：#