Alias: Rutoside , Violaquereitrin
Chemical name: 4H-1-Benzopyran-4-one ,3 -[(6-O-(6-deoxy-α-L-mannopyranosyl)-β-D- glucopyranosyl ]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy
Molecular formula & Molecular weight: C27H30O16:610.51
Properties: light yellow needle-like crystal(water), Melting point 176-8oC, []23D +13.82oC(ethanol),[]20D -39.43oC(pyridine).1g in 7ml methanol, 8000ml water, 200ml Boiling water. UVλ CH3OH max nm:258.361. IRνKBr max cm-1 :3400(OH), 1670(C=O), 1620, 1520, 1470(C6H5-) .
Plant origin: Ruta graveolens L., Scphora japonica L., Hypericum aseyron L., Berchemia polyphylla Wall, var leioclada Hand. - Mazz . , Mallotus japonicus Muell . - Arg , Fagopyrum esculentum Moench .
Functions and Uses:
1, anti-inflammatory Functions : it can control the inflammatory caused by wool ball in rats. Sod. rutin sulfate in this product can extremely control the inflammatory of fever edema of rats.
2, Function of vitamin P: It can keep vascular resistance, reduce its permeability and brittleness; it can lower fat of fatty liver and offer better effects if working with glutathione.
3, antivirus : in 200μg/ml, it can restrain the activity of vesicular stomatitis virus.
4, restrain the activity of aldose reductase :95% restrain percent in 10-5M , so it can help the therapy of Diabetes mellitus.
5, toxicity: mouse LD50 950mg/kg.
6, Clinic application: Used to prevent stroke, hypertension, retinal hemorrhage, purpura, and acute hemorrhagic nephritis. The treatment of chronic bronchitis, efficiency reaches 84.8% and 98%. . Troxerutin as its derivatives used in the treatment of burns, arthritis & all kinds of vascular disease, has been the sale of goods abroad. China also produces this drug:The efficiency for cerebrovascular disease 87.8%, cure retinal edema and bleeding 88%.