80621-81-4 Rifaximin Rifaximin Price
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Rifaximin Basic information:
Product Name: Rifaximin
CAS: 80621-81-4
Synonyms: XIFAXAN;,20,22,24,26-octamethyl-,(2s-(2r*,16z,18e,20r*,21r*,22s*,23s*,24s*,25r*,26s*,;2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-e)pyrido(1,2-a)benzimidaz;28e))-27r;fatroximin;l105;l105(ansamacrolideantibiotic);l105sv
MF: C43H51N3O11
MW: 785.88
EINECS:
Product Categories: Active Pharmaceutical Ingredients;Antibacterial;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents
Mol File: 80621-81-4.mol
Rifaximin Chemical Properties:
mp 200-2050C (dec)
storage temp. 0-6°C
Specifications of analysis:
Item |
Specifications |
Results |
Characters |
Red-orange to dark,crystalline powder |
Red-orange crystalline powder |
PH |
Take sample, add water into each 1 ml contains about 10mg of suspension, according to the determination should be 4.5~7.5 |
6.4 |
Identification 1)Chemical
2)HPLC
3)IR
|
Identification reaction for ferric chloride, A brownish-black colour is produced. The retention time of principal peak of substance being examined in the chromatogram obtained in the assay is identical with that of standard solution. The infrared absorption spectrum is concordant with reference spectrum of Rifaximin. |
Confirm
Confirm
Confirm
|
Test 1)Crystallinity 2)Loss on drying 3)Related substance
4)Residue on ignition 5)Heavy metals 6)Solvent residue
7)Microbial limit tests Total microbial count Mould and yeast E.coli |
Should meet the requirements. Not more than 4.5%. Individual impurity not more than 1.5%, Total impurities not more than 3.0%. Not more than 0.1%. Not more than 0.002%. Ethanol Not more than 0.5% Dichloromethane Not more than 0.06%
Not more than 1000cfu/g Not more than 100cfu/g Absence per g Not detected |
Confirm 1.7% Confirm Confirm 0.03% Confirm Confirm Not detected
Confirm Confirm Confirm |
Assay |
Not less than 98% (anhydrous substance) |
98.9% |
Conclusion |
The results conforms with Enterprise standards |
d sulfuric acid
.
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