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150399-21-6 Balsalazide disodium Balsalazide disodium Price
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BALSALAZIDE DISODIUM HYDRATE |
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PRODUCT IDENTIFICATION |
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CAS NO. |
80573-04-2; 82101-18-6 (Base) |
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EINECS NO. |
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FORMULA |
C17H13N3O6Na2.2H2O |
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MOL WT. |
437.32 |
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H.S. CODE |
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TOXICITY |
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SYNONYMS |
Balsalazida; Balsalazide; Balsalazido; |
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5-((1E)-(4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid disodium salt hydrate; Balsalazidum; |
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PHYSICAL AND CHEMICAL PROPERTIES |
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PHYSICAL STATE |
yellow to orange crystalline powder |
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SOLUBILITY IN WATER |
freely soluble (soluble in methanol) |
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STABILITY |
Stable under ordinary conditions. Hygroscopic. |
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GENERAL DESCRIPTION & APPLICATIONS |
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Balsalazide disodium liberates 5-aminosalicylic acid in colonic lumen by enzymatic action for colitis therapy. It is a prodrug of mesalamine (5-aminosalicylic acid) which is an anti-inflammatory drug used to treat inflammation of inflammatory bowel disease and mild to moderate ulcerative colitiswhich leads to flare-ups (bouts or attacks) of bloody diarrhea, abdominal cramps, and fever. |
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SALES SPECIFICATION |
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APPEARANCE |
yellow to orange crystalline powder |
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IDENTIFICATION |
passes Test A,B |
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ASSAY |
98.0 - 102.0% as dried basis |
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WATER |
8.0 - 10.0% max |
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CLARITY OF SOLUTION |
Clear to amber solution |
d sulfuric acid
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