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palmitoylethanolamide 544-31-0 palmitoylethanolamide 544-31-0
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Description
Palmitoylethanolamide (PEA) is an endogenous fatty acid amide, belonging to the class of nuclear factor agonists. PEA has been demonstrated to bind to a receptor in the cell-nucleus (a nuclear receptor) and exerts a great variety of biological functions related to chronic pain and inflammation. The main target is thought to be the peroxisome proliferator-activated receptor alpha (PPAR-α). However, the presence of PEA (and other structurally related N-acylethanolamines) has been known to enhance anandamide activity by a so-called "entourage effect".
Product Name |
Palmitoylethanolamide |
Appearance |
White to off-white powder |
CAS NO. |
544-31-0 |
Molecular Formula |
C18H37NO2 |
Molecular Weight |
299.49 |
Specification
Item |
Specifications |
Results |
||
Assay(%, On Dried base) |
NLT98.0% |
98.58% |
||
Appearance |
Fine Powder |
Complies |
||
Color |
White to Off-White |
Complies |
||
Identification |
Positive |
Complies |
||
Loss on Drying |
1.0% Max |
0.28% |
||
Residue on ignition |
0.1% Max |
0.04% |
||
Particle size |
D(0.5): 3μm |
D(0.569): 3μm |
||
|
D(0.99): 10μm |
D(0.995): 10μm |
||
Excipients |
None |
Conform |
||
|
||||
Heavy Metals |
NMT10 ppm |
Conforms |
||
Lead(Pb) |
NMT1ppm |
Conforms |
||
Arsenic(As) |
NMT1ppm |
Conforms |
||
Mercury(Hg) |
NMT0.1ppm |
Conforms |
||
Cadmium(Cd) |
NMT1ppm |
Conforms |
||
Sulfate(SO4) |
NMT0.040% |
Conforms |
||
Chloride(Cl) |
NMT0.020% |
Conforms |
||
Solvent Residual |
Meeting USP Standard |
Conforms |
||
|
||||
Total Plate Count |
10,000cfu/g Max |
Conforms |
||
Yeast & Mold |
300cfu/g Max |
Conforms |
||
Coliforms |
10cfu/g Max |
Conforms |
||
E.Coli |
Negative/10g |
Negative |
||
Salmonella sp. |
Negative/25g |
Negative |
||
Staph Aureus |
Negative/10g |
Negative |
||
Pseudomonas aeruginosa |
Negative/25g |
Negative |
||
Conclusion |
The results conforms with Enterprise standards |
Function
Palmitoylethanolamide (PEA) has been shown to have anti-inflammatory, anti-nociceptive, neuroprotective, and anticonvulsant properties.
Storage
Stored in a dry and cool place, keep away from strong light and heat
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