Clearance Sale: 98% Purity API Powder CAS 305-03-3 C14H19Cl2NO2 Chlorambucil

Min.Order / FOB Price:Get Latest Price

10 Gram	FOB Price:USD 7.0000 -15.0000

10 Gram

FOB Price:USD 7.0000 -15.0000

Min.Order :10 Gram
Purity: 98% HPLC
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

Chlorambucil Chlorambucil API 305-03-3

Quick Details

Appearance:white powder
Application:treat chronic lymphocytic leukemia
PackAge:poly bag + foil bag
ProductionCapacity:100|Kilogram|Month
Storage:RT
Transportation:express via fedex, dhl, ems,etc

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Clearance Sale: 98% Purity API Powder CAS 305-03-3 C14H19Cl2NO2 Chlorambucil

Chlorambucil is a nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens;

Chlorambucil is an Alkylating Drug. The mechanism of action of chlorambucil is as an Alkylating Activity;

Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.

Details:

Chlorambucil is a chemotherapy medication used to treat chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, and non-Hodgkin lymphoma. For CLL it is a preferred treatment. It is given by mouth.

Common side effects include bone marrow suppression. Other serious side effects include an increased long term risk of further cancer, infertility, and allergic reactions. Use during pregnancy often results in harm to the baby. Chlorambucil is in the alkylating agent family of medications. It works by blocking the formation of DNA and RNA.

Chlorambucil was approved for medical use in the United States in 1957. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.

Chlorambucil's current use is mainly in chronic lymphocytic leukemia, as it is well tolerated by most patients, though chlorambucil has been largely replaced by fludarabine as first-line treatment in younger patients. It can be used for treating some types of non-Hodgkin lymphoma, Waldenström macroglobulinemia, polycythemia vera, trophoblastic neoplasms, and ovarian carcinoma. Moreover, it also has been used as an immunosuppressive drug for various autoimmune and inflammatory conditions, such as nephrotic syndrome.

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