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22254-24-6 Ipratropium bromide Ipratropium bromide Price
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Description
Ipratropium bromide is a mAChR M (muscarinic) antagonist, bronchodilator. N-Isopropyl salt of atropine.
Specification
Item |
Specification |
Result |
Characters |
||
Appearance |
White or almost white, crystalline powder |
white powder |
Solubility Test |
soluble in water, freely soluble in methanol, slightly soluble in ethanol 96% |
Complies |
Identification |
||
IR |
Compare to standard spectrum |
Complies |
Bromide test |
Positive test for bromide |
Positive |
Tests |
||
Appearance of solution |
Solution S is clear and not more intensely colored than reference solution GY7 |
Complies |
Melting point |
Melts at about 230°C with decomposition |
Complies |
PH |
pH5.0~7.5 |
5.58 |
Impurity A(TLC) |
Not more than 0.1% |
Complies |
Related substances(by HPLC) |
||
Impurity B |
Not more than 0.1% |
0.01%(BDL) |
Impurity C |
Not more than 0.1% |
Not detected |
Impurity D |
Not more than 0.05% |
0.01%(BDL) |
Impurity E |
Not more than 0.1% |
Not detected |
Impurity F |
Not more than 0.1% |
Not detected |
Single max unknown impurities |
Not more than 0.1% |
Not detected |
Total impurities |
Not more than 0.25% |
0.02% |
Loss of drying |
Between 3.90% to 4.40% w/w |
4.13% |
Sulphated Ash |
≤0.1% |
0.05% |
Assay(on anhydrous basis)(by potentionmeter) |
Assay between 99.0%-100.5% |
100.28% |
CAS NO:30123-17-2
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
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