42971-09-5 Vinpocetinum Vinpocetinum Price
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Product name | Vinpocetine |
Another name | Eburnamenine-14-carboxylic acid ethyl ester; |
(3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester; | |
CAS | 42971-09-5 |
MF | C22H26N2O2 |
Appearance | White crystalline solid |
Exact mass | 350.199 |
logP | 4.0862 |
PSA | 34.47 |
melting point | 147-153ºC dec |
boiling point | 419.5ºC at 760 mmHg |
Water solubility |
practically insoluble in water,soluble in methylene chloride,slightly soluble in anhydrous ethanol |
Introduction | |
A derivative of Vincamine with vasodilating activity. Vasodilator (cerebral). | |
Application | |
It is used to improve the sequelae of cerebral infarction, sequelae of cerebral
hemorrhage, cerebral arteriosclerosis and other symptoms induced. |
Items | Specification(BP2000) | Results |
appearance | White or slightly yellow, crystalline powder | White crystalline |
Solubility |
Practically insoluble in water, soluble in methylene chloride, slightly soluble in anhydrousethanol |
confirms |
Identification (IR) |
same wave numbers as that of the Vinpocetine, CRS similarly prepared |
Conforms |
CRS similarly prepared. | ||
Specific Optical Rotation (On dried basis) |
Between +127° and +134° | +132.7° |
Related Substances (External Standard method) | ||
Ethyl vincaminate(A) | ≤0.6% | Conforms |
Apovincamine(B) | ≤0.5% | Conforms |
Methoxyvinpocetine(C) | ≤0.3% | Not detected |
Dihydrovinpocetine(D) | ≤ 0.5% | Not detected |
Other single impurity | ≤0.10% | Conforms |
Total impurity | ≤ 1.0% | 0.19% |
Loss on drying | ≤ 0.5% | 0.04% |
Sulphated ash | ≤ 0.1% | 0.07% |
Assay(On dried basis) | 98.5% ~101,5% , | 100.20% |
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