8025-81-8 Spiramycin Spiramycin Price
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Spiramycin 8025-81-8
CAS NO : 8025-81-8
Synonyms :
Foromacidin
Leucomycin
Provamycin
Rovamycin
Spiramycin base
Molecular Formula : C43H74N2O14
Molecular Weight : 843.0
Assay : Not less than 4100iu/mg calculated with reference to the anhydrous substances
Appearance: A white or slightly yellowish powder
TEST ITEMS |
SPECIFICATIONS |
|
Appearance |
A white or slightly yellowish powder |
|
Identification A. UV Spectrum
B. TLC C. Color Reaction |
The specific absorbance at the maximum (232nm) is about 340. Corresponds to reference solution. Brown colour.
|
|
pH |
8.5-10.5 |
|
Specific optical rotation |
-80°- -85°(dried substance) |
|
Composition (HPLC) |
SpiramycinⅠ≥80.0 % SpiramycinⅡ≤5.0 % SpiramycinⅢ≤10.0 % Total Spiramycins ≥90.0 % |
|
Related substances (HPLC) |
Any single impurity≤2.0 % |
|
Heavy metals |
≤20ppm |
|
Loss on drying |
≤3.5 % |
|
Sulphated ash |
≤0.1 % |
|
Assay (wet substance) |
No limits (IU/mg) |
|
Assay (dried substance) |
≥4100 IU/mg |
CONCLUSION |
CONFORM TO EP VII |
Function:
This product can be used for the infections in ears, nasus, larynx and respiratory tract systemcaused by gram-positive bacterium and some gram-negative bacterium such as acute bronchitic, acute bout of acute bronchitis,
pneumonia, scarlet fever, tonsillitis, tympanitis, periodontitis and acute nososinusitis. It also shows suitable to non-gonococcal urethritis. It possesses strong internal antibacterial function and Post-Antibiotic Effect (PAE).
It’s able to improve the phagocytosis of phagocyte and is widely distributed in body. The concentration in
histiocyte is higher than erythromycin and is less adverse reaction as well.
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