129-06-6 Warfarin sodium Warfarin sodium Price
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Appearance: Colourless, odourless crystals. Soluble in common organic solvents and alkaline media; insoluble in water and hydrocarbon solvents. Used as a rodenticide. UN covers coumarin derived pesticides, solid, toxic.
It is a low acute toxicity, chronic toxicity of high, continuous medication, it will act for several times until death of the first generation anticoagulant rodenticides. It is good for Palatability, generally do not produce antifeedant. Scope applicable to residential areas, warehouses, ships, docks, poultry farms and other prevention and control rats, mice, Ryukyu Mouse and other rodents.
Item |
Specifications |
Result |
Description |
White crystalline powder |
Conforms |
Identification |
a. IR spectrum exhibits maximum only at the same wavelengths as that of the USP reference standard |
Conforms |
b. Melting range of the obtained warfarin: 157° to 167°(range should not exceed 4°) |
160°~162° |
|
c. A solution of it responds to the test for sodium. The filtrate obtained in identification B responds to the flame test for sodium. |
Conforms |
|
PH |
7.2 to 8.3 (1 in 100solution) |
8.0 |
Water |
≤0.3% |
0.10% |
Heavy metals |
≤10ppm |
Conforms |
Absorbance in alkaline solution |
≤0.1 |
0.09 |
Chromatographic purity |
Individual known impurity≤0.3% |
0.003% |
Individual unknown impurity≤0.1% |
0 |
|
Total impurity≤1.0% |
0.006% |
|
Isopropyl alcohol content |
8.0%~8.5% |
8.26 |
Organic volatile impurity |
Comply the USP requirements |
Conforms |
Residual solvents |
Ethanol ≤1000ppm |
Conforms |
Acetone ≤1000ppm |
Conforms |
Function
Applicable to the prevention and treatment of thromboembolic disease. Only effective oral, work slow and sustained, long-term anticoagulation is required to use this product, quickly when anticoagulant, heparin should be used, or heparin therapy based on the use of this product.
1. Prevention and treatment of thromboembolic disease, prevents thrombus formation and development, such as the treatment of thromboembolic venous inflammation, reduce morbidity and mortality in pulmonary embolism to reduce surgical operation, rheumatic heart disease, hip surgery, an artificial replacement heart valve surgery, such as the incidence of venous thrombosis.
2. auxiliary Therapeutics of myocardial infarction.
Application
Warfarin is an anticoagulant. It was initially marketed as a pesticide against rats and mice and is still popular for this purpose. A few years after its introduction, warfarin was found to be effective and relatively safe for preventing thrombosis and embolism (abnormal formation and migration of blood clots) in many disorders. It was approved for use as a medication in the early 1950s and has remained popular ever since; warfarin is the most widely prescribed anticoagulant drug in North America.
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CAS NO:30123-17-2
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
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