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TPGS is a derivation of natural vitamin E. It is a esterification product of natural Vitamin E Acid Succinate and Polyethylene Glycol. Natural Vitamin E TPGS is soluble completely in water and produces a clarification and transparence solution. The max solubility of Natural Vitamin E TPGS is 25%.
Application
Pharmaceuticals: 1) Improving drug bioavailability 2) Emulsion vehicle 3) Functional ingredient in self-emulsifying formulations 4) Reducing drug sensitivity on skin or tissues
Food and beverages: 1) Liquid vitamin E or liquid multivitamin/mineral supplements 2) Other forms of vitamin E or multivitamin/mineral dietary supplements such as tablets, softgels, bars and others.
Personal Care and Cosmetics: 1) Cream, lotions and other products for topical application of vitamin E and other formulated actives. 2) Eye drops, nasal sprays, syrups and others primarily in formulating active compounds.
Specification
Product and Batch Information |
||||
|
Products Name: |
Vitamin E Polyethylene Glycol Succinate(TPGS) |
Manufacture Date: |
Dec. 20, 2014 |
|
Specification: |
USP36 |
Analysis Date: |
Dec. 18, 2017 |
|
Batch No: |
20171218 |
Report Date: |
Dec. 19, 2017 |
|
Analysis: |
320KG |
Expiry Date: |
Dec. 20, 2017 |
Analysis Item |
Specification(USP36) |
Result |
||
Appearance |
White to Yellowish, waxy solid Soluble in ethanol, insoluble in hexane |
Almost white waxy solid |
||
Identification(GC) |
The retention time for the major peak of the test solution corresponds to that in the standard solution, as obtained in the test for content |
Conform |
||
Water-solubility |
Meets the requirements |
Conform |
||
Acidity |
≤0.27ml |
0.14ml |
||
Specific rotation |
≥+24.0° |
+25.2° |
||
Assay |
D-alpha tocopherol (C29H50Q2)≥25.0% |
26.4% |
||
Residual Solvents |
Ethanol≤0.5%
|
<0.05% |
||
Toluene≤0.089% |
<0.0089% |
|||
Hexane≤0.029% |
<0.0029% |
|||
Butanone≤0.5% |
<0.05% |
|||
Total Aerobic bacterial count |
≤1000cfu/g |
Complies |
||
Yeasts and Moulds |
≤100cfu/g |
Complies |
||
Escherichia coli |
Negative |
Negative |
||
Salmonella species |
Negative |
Negative |
||
Psendomonas aeruginosa |
Negative |
Negative |
||
Staphylococcus aureus |
Negative |
Negative |
||
Conclusion |
Conform to USP36 |
CAS NO:30123-17-2
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
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