- Min.Order :0
- Purity: 98%
Keywords
GBR-12935 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine
Quick Details
- Appearance:Solid powder
- Application:GBR 12935 is a piperazine derivative and a potent and selective inhibitor of dopamine uptake with IC50 value of 3.7nM. It is found to have multiple binding sites in rat and human brains. It was or...
- PackAge:inquiry
- ProductionCapacity:
- Storage:-20°C Freezer
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Details:
GBR 12935 inhibits DA uptake with IC50 value of 3.7nM in vitro. It elevated locomotion to a greater extent in C57BL/6J mice at the maximally active dose of 10 mg/kg in vivo. It shows a Kd value of 1.08nM in dopamine transporter transfected COS-7 cells.
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