CasNo.857290-04-1,PF 915275,N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide(857290-04-1) Suppliers

0	Negotiable

Min.Order :0
Purity: >98 %

Keywords

PF 915275 N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide

Quick Details

Appearance:Solid powder
Application:PF-915275 is a selective and potent and inhibitor of human 11β-hydroxysteroid dehydrogenase type 1(11βHSD1) inhibitor with Ki 2.3 nM. It has good preclinical pharmacokinetic properties. It inhib...
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Storage:-20°C Freezer
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Superiority:

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

Details:

PF-915275 inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro and has antidiabetic activity in vivo. It has an excellent pharmacokinetic profile characterized by low clearance, long half-life and good oral bioavailability.