CHIR-090 N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide
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CHIR-090 displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. It has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli by inhibiting Lp
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