SPP 86

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Purity: ≥98% by HPLC

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SPP 86 1-(1-Methylethyl)-3-(2-phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

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Application:SPP 86 is a potent and cell-permeable RET inhibitor (IC50 = 8 nM). It also inhibits EphA1, FGFR1, Flt4, Lck and Yes. SPP 86 suppresses the proliferation of HCT 116 and TPC1 cells in vitro.
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

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